Abstract
We have shown that in C57BL6J adult mice repeated cold stress results in cold acclimation (1). Cold stress was provided by placement of mice for 3 hours at 2-wk intervals for 3 occasions in individual restrainers that prevented gross motor activity in the 6°-10°C environment (2). Cold acclimation was evidenced by a greater cold tolerance (reduced rate of decline of colonic temperature) and increased heat production in the third test relative to the first. We also reported that aged mice have poorer cold tolerance (higher rate of decline of colonic temperature) than adults and demonstrate a reduced ability to increase heat production in response to cold stress. Moreover, repeated cold stress tests fail to improve cold tolerance and to increase heat production in aged mice (3).
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© 1994 Birkhäuser Verlag Basel
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Talan, M.I., Kirov, S.A. (1994). Sympathetic Outflow to Brown Adipose Tissue and Metabolic Heat Production in Adult, Aged, and Cold-Acclimated Adult Mice. In: Zeisberger, E., Schönbaum, E., Lomax, P. (eds) Thermal Balance in Health and Disease. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7429-8_14
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DOI: https://doi.org/10.1007/978-3-0348-7429-8_14
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7431-1
Online ISBN: 978-3-0348-7429-8
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