Abstract
Patient was a 60-year-old woman with Follicular lymphoma, treated with Fludarabine and Rituximab and then started on Rituxan, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for six cycles. Patient complained of multiple episodes of palpitation after starting R-CHOP treatment. Follow up Holter monitor revealed multiple brief episodes of symptomatic non-sustained Ventricular tachycardia (NSVT). She was started on metoprolol. She continued her treatment with Rituximab while she was on metoprolol. After completion of Rituximab maintenance treatment, her lymphoma was in remission, metoprolol stopped and there was no recurrence of symptomatic arrhythmia.
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References
Poterucha JT, Westberg M, Nerheim P, Lovell JP. Rituximab-induced polymorphic ventricular tachycardia. Tex Heart Inst J. 2010;37(2):218–20.
Zamorano JL, Lancellotti P, Rodriguez Muñoz D, et al. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: the Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC) [published correction appears in Eur Heart J. 2016 Dec 24]. Eur Heart J. 2016;37(36):2768–801.
Millward PM, Bandarenko N, Chang PP, et al. Cardiogenic shock complicates successful treatment of refractory thrombotic thrombocytopenia purpura with rituximab. Transfusion. 2005;45(9):1481–6. https://doi.org/10.1111/j.1537-2995.2005.00560.
Ostenfeld EB, Erichsen R, Pedersen L, Farkas DK, Weiss NS, Sørensen HT. Atrial fibrillation as a marker of occult cancer. PLoS One. 2014;9(8):e102861.
Buza V, Rajagopalan B, Curtis AB. Cancer treatment–induced arrhythmias. Circul Arrhyth Electrophysiol. 2017;10(8)
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Rohani, A. (2021). Rituximab, Doxorubicin or Cancer Induced Tachycardia. In: Clinical Cases in Cardio-Oncology. Clinical Cases in Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-71155-9_8
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DOI: https://doi.org/10.1007/978-3-030-71155-9_8
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