Abstract
Patient was a 35-year-old male with Testicular germ-cell cancer, (TGCC) with no cardiovascular risk factors.
Ten days after fourth course of Bleomycin, Etoposide and Cisplatin (BEP) therapy, he presented to the emergency department with acute chest pain and significant ST segment depression in anterior leads. Coronary angiogram revealed 95% proximal stenosis of the left anterior descending artery. Patient underwent thrombus aspiration and percutaneous coronary intervention was performed with a drug eluting stent.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
de Zwaan C, Bär FW, Wellens HJ. Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infarction. Am Heart J. 1982;103(4 Pt 2):730–6.
van den Belt-Dusebout AW, Nuver J, de Wit R, et al. Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer. J Clin Oncol. 2006;24(3):467–75.
Fung C, Fossa SD, Milano MT, Sahasrabudhe DM, Peterson DR, Travis LB. Cardiovascular disease mortality after chemotherapy or surgery for testicular nonseminoma: a population-based study. J Clin Oncol. 2015;33(28):3105–15.
Lauritsen J, Hansen MK, Bandak M, et al. Cardiovascular risk factors and disease after male germ cell cancer. J Clin Oncol. 2020;38(6):584–92.
Herrmann J. Vascular toxic effects of cancer therapies. Nat Rev Cardiol. 2020;17:503–22.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Rohani, A. (2021). Cisplatin Induced Acute Coronary Syndrome. In: Clinical Cases in Cardio-Oncology. Clinical Cases in Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-71155-9_13
Download citation
DOI: https://doi.org/10.1007/978-3-030-71155-9_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-71154-2
Online ISBN: 978-3-030-71155-9
eBook Packages: MedicineMedicine (R0)