Abstract
Pulse, respiration, temperature, and blood pressure or “vital signs” are routinely performed as part of the cardiovascular assessment and considered the earliest objective fundamental aspect of the physical examination. The term “vital signs” specifies the presence of those bodily functions considered an essential component of life. These signs are historically important to recognize and provide important insights into methods and techniques for diagnosing various disease states. These objective findings along with other key components assist clinicians in narrowing the differential diagnosis or determining the cause of the underlying disease. Included in this discussion are signs found in patients with hyperthyroidism as detected by blood pressure and temperature as well as bleeding disorders that may be surreptitiously discovered when blood pressure is measured using a sphygmomanometer cuff. Additionally, some of these signs may be clinically useful providing important insights into potential mechanisms of disease. Thus, it is important that clinicians learn how to properly perform, identify, and apply these signs. Included in this chapter on vital signs is a brief historical background of the person who described the sign, the sign as originally described, and if available, the sensitivity, specificity, and predictive values of the signs.
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References
Seguin E. The use of the thermometer in clinical medicine. Chicago Med J. 1866;23:193–201.
Cushing H. On routine determinations of arterial tension in operating room and clinic. Boston Med Surg J. 1903;148(10):250–6.
Skinner HA. The Origin of Medical Terms. Baltimore: Williams & Wilkins; 1949.
Neff T. Routine oximetry: a fifth vital sign? Chest. 1988;94(2):227.
Bruwer AJ. Classic Descriptions in Diagnostic Roentgenology, vol. 2. Springfield: Charles C. Thomas; 1964.
B. RW. Medical eponym: Rumpel-Leede sign. N Engl J Med. 1944;230(4):122–3.
Kast A, Rumpel T, Fraenkel E. Pathologisch-anatomische Tafeln nach frischen Präparaten mit erläuterndem anatomisch-klinischem Text. Hamburg: Staatskrankenhäusern-Wandsbeck-Hamburg; 1909.
Rumpel T. Photographien von Scharlachkranken mit multiplen Hautblutungen. Deutsche med Wchenschr. 1909;35:2297.
[No author]. Directory of Medical Specialists Certified by American Boards, vol. 8. Chicago: Advisory Board for Medical Specialties; 1957.
Leede C. Hautblutungen, durch Stauung hervorgerufen als diagnostisches Hilfsmittel. München med Wochenshr. 1911;58:293–5.
Hess AF, Fish M. Infantile scurvy: the blood, the blood–vessels and the diet. Am J Dis Child. 1914;8(6):385-405.
Wang K, Lee J. Rumpel-Leede sign. N Engl J Med. 2014;370(1):e1.
Saraf S. Tourniquet induced purpura during hand surgery: a case report. Internet J Hand Surg. 2016;7(1):1–4.
Varela D, Tran D, Ngamdu KS, Trullender B, Mukherjee D, Abbas A. Rumple-Leede phenomenon presenting as a hypertensive urgeny. Proc Bayl Univ Med Cent. 2016;29(2):200–1.
Antunes AC, Oliveira GL, Nunes LI, Guedes Filho LA, Prado RS, Henriques HR, Vieira AJC. Evaluation of the diagnostic value of the tourniquet test in predicting severe dengue cases in a population from Belo Horizonte, State of Minas Gerais, Brazil. Rev Soc Bras Med Trop. 2013;46(5):542–6.
Dubach PI, Mantokoudis G, Lammie B. Rumpel-Leede sign in thrombocytopenia due to Epstein-Barr virus-induced mononucleosis. Br J Haematol. 2010;148(1):2.
Duncan SC, Winkelmann RK. Early histopathology of the cutaneous capillary fragility test (Rumple-Leede). J Cutan Pathol. 1979;6(1):1–4.
Castiglioni diArture. Grocco, Pietro. Cesare Patrizi. Enciclopedia italiana. 1933. Treccani. http://www.treccani.it/enciclopedia/pietro-grocco_%28Enciclopedia-Italiana%29/. Accessed 2 Oct 2020.
[No author]. Notes. Nature. 1916;97:42–3.
Fantini B. Polio in Italy. Dynamis. 2012;32(2):329–59.
Frugoni C, Giugni E. Le signe du lacet dans les maladies à manifestations hemorragiques. Semaine méd. 1911;31(3):25–8.
Italo Vittorio Tondi. Cesare Frugoni Un Principe Della Medicina Clinica. 2000. http://www.bpp.it/Apulia/html/archivio/1995/I/art/R95I028.html. Accessed 2 Oct 2020.
Frugoni C. Di Giuseppina Bock Berti. Dizionario Biografico degli italiana, vol. 56. 1998. http://www.treccani.it/enciclopedia/cesare-frugoni_(Dizionario-Biografico)/. Accessed 2 Oct 2020.
[No author]. Presentation of honorary fellowship in the American Academy of Allergy to Professor Cesare Frugoni in Rome, Italy. J Allergy. 1951;22(4):381–2.
Koren N. Jewish Physicians: A Biographical Index. Jerusalem: Israel Universities Press; 1973.
Edmond Weill Geni @ 2019 Geni.com. https://www.geni.com/people/Edmond-Weill/375474846080003021. Accessed 12 Sep 2019.
[No author]. Death of Prof. E. Weill. Am J Dis Child. 1924;29(4):523.
Barrier G, Weill E. Committee on Historical and Scientific Works. Institute attached to the National School of Charters. Last updated on 20/08/2019. https://cths.fr/an/savant.php?id=4988. Accessed 10 Aug 2019.
Weill E. Wikipédia. https://fr.wikipedia.org/wiki/Edmond_Weill. Accessed 10 Jul 2019.
Chalier JF. Les ictères hémolytiques. Lyon: Imprimeries Réunies; 1909.
[No author]. Joseph Chalier (1884–1942). Presse Méd. 1942;51:573.
Weill E, Chalier J. Purpura provoqué par hypertension veineuse. Bull Soc Med d Hosp de Lyons. 1911;10:167–72.
Lucatello L. Stefano Arieti Dizionario Biografico degli Italiani. Treccani. 2006. http://www.treccani.it/enciclopedia/luigi-lucatello_(Dizionario-Biografico)/. Accessed 10 Aug 2019.
Bonati MR, Zampieri F, Zanatta A. Per una storia della medicina. In: Selezione di Lavori del Gruppo di Medicina Umanistica, Universitá degli studi di Padova, 2010–2011. Padova: Libraria Padovana Editrice; 2012.
Lucatello L. Per la sintomatologia endocrina. In: Lavori dei Congressi di medicina interna, XXIII Congresso (1913, Roma). Roma; 1914. p. 328.
Gregorio M. The sign of Lucatello. Endocr Surv. 1928;5:399–401.
Nicola Pende’s birthplace. Himetop: the history of medicine topographical database. http://himetop.wikidot.com/nicola-pende-s-birthplace. Accessed 10 May 2020.
Pende, Nicola di Emmanuel Betta-Dizionario Biografico degli Italiani. 2015;82. Treccani. http://www.treccani.it/enciclopedia/nicola-pende_%28Dizionario-Biografico%29/. Accessed 15 May 2020.
Assegnazione di premi. Gazzetta degli ospendall e delle cliniche. 1904;25. https://play.google.com/books/reader?id=76rwjXM4ELwC&printsec=frontcover&output=reader&hl=en&pg=GBS.PP855. Accessed 15 May 2020.
[No author]. Medical news: foreign university intelligence. Lancet. 1908;1:824.
Pende N. Endocrinologia: Patologia e Clinica degli Organi a Secrezione Interna. Milan: Vallardi Endocrinology; 1916.
Strategie politiche ed esignenze scientificheL il ruolo di Nicola Pende nel’instituzione e nell’organizzazione dell’Universita di Bari Annali di Storia delle Universita Italiane. 2013;17. http://www.cisui.unibo.it/annali/17/testi/03_Dell_Era_frameset.htm. Accessed 15 May 2020.
Nicola Pende, la via italiana al razzismo. Quotidiano di Bari. 2018. https://quotidianodibari.it/nicola-pende-la-via-italiana-al-razzismo/. Accessed 15 May 2020.
Gronch G. Bari cancella via Nicola Pende. 2006. http://www.lagazzettadelmezzogiorno.it/news/home/44099/bari-cancella-via-nicola-pende.html?refresh_ce. Accessed 15 May 2020.
[No author]. New items: award to Pende. N York M J. 1929,112:197.
[No author]. Prize to Pende. JAMA. 1920;75:115.
Levi-Montalcini R. Elogio dell'imperfezione. Milano: Garzanti; 1987.
Bari cancella via Nicola Pende la Gazzetta del Mezzogiorno.it. Sabato 07 Luglio 2018. http://www.lagazzettadelmezzogiorno.it/news/home/44099/bari-cancella-via-nicola-pende.html. Accessed 15 May 2020.
Rome to remove race law signatories. ANSA en Politics. 2018. http://www.ansa.it/english/news/politics/2018/01/22/rome-to-remove-race-law-signatories_da4c7f1b-1743-47d9-8434-52aac7230c0c.html. Accessed 15 May 2020.
Pende N. Sopra una triade sintomatica dell’ipertiroidismo costituzionale: sua importanza diagnostica nelle forme larvate di tireotoxicosi. Endocrinol Patol Costit. 1926;1:311–2.
Nicola pen scienziato razzista. La Repubblica Archivivio. 2006. http://ricerca.repubblica.it/repubblica/archivivio/repubblica/2006/09/14/nicola-pend-scienziato-razzista.html. Accessed 15 May 2020.
ARCA centro di iniziativa democratica. Elimare dalla toponomastica barese via Nicole Pende. 2018. http://wwwarcabari.it/2013/02/eliminare-dalla-toponomastica-barese-via-nicola-pende/. Accessed 15 May 2020.
Birrer RB, Birrer CD. Medical Diagnostic Signs: A Reference Collection of Eponymic Bedside Signs. Illinois: Charles C. Thomas Publishers; 1982.
Marcucci L. Handbook of Medical Eponyms. Baltimore: Lippincott Williams & Wilkins; 2002.
White FA. Physical Signs in Medicine and Surgery: An Atlas of Rare, Lost and Forgotten Physical Signs. Ocala: Museum Press Books; 2009.
Pollock SG. Pressure tracings in obstructive cardiomyopathy. N Engl J Med. 1994;331:238.
Grossman W. Profiles in dilated (congestive) and hypertrophic cardiomyopathies. In: Grossman W, editor. Cardiac Catheterization and Angiography. Philadelphia: Lea & Febiger; 1986. p. 420–1.
Cui H, Nguyen A, Schaff HV. The Brockenbrough-Braunwald-Morrow sign. J Thorac Cardiovasc Surg. 2018;156(4):1614–5.
Criley JM, Goldberg SL, French WJ. The Brockenbrough-Braunwald-Morrow sign. N Engl J Med. 1994;331:1589–90.
Dorland WAN. Dorland’s Illustrated Medical Dictionary. 32nd ed. Philadelphia: Elsevier Saunders; 2012. p. 251.
Brockenbrough EC, Braunwald E, Morrow AG. A hemodynamic technic for the detection of hypertrophic subaortic stenosis. Circulation. 1961;23(2):189–94.
Edwin C. Brockenbrough, MD, Medical Director, Pacific Vascular/PVICME. Pacific Vascular Incorporated. 2016. http://www.pvicme.com/faculty.htm. Accessed 3 Mar 2020.
[No author]. Seattle Surgical Society. Northwest Med. 1972;71:333.
Edwin C. Brockenbrough, MD, FACS. Marquis who’s who. Humanitarian award. https://worldwidehumanitarian.com/2017/02/20/edwin-brockenbrough/. Accessed 3 Mar 2020.
Eugene Braunwald, MD, MACC, A lifetime of achievements and a legend of cardiology. American College of Cardiology Dec 27, 2014. Cardiology magazine. https://www.acc.org/latest-in-cardiology/articles/2014/02/27/13/20/eugene-braunwald-md-macc-a-lifetime-of-achievements-and-a-legend-of-cardiology. Accessed 8 Aug 2019.
Nicholls M. Eugene Braunwald MD: an icon of the 20th century still going strong. Eur Heart J. 2015;36(22):1350–1.
Cohn LH. Eugene Braunwald, MD. J Thorac Cardiovasc Surg. 2013;146(4):743–4.
Dr. Eugene Braunwald, World-renowned cardiologist, to Speak at Miller School on April 18. University of Miami Miller School of Medicine. http://med.miami.edu/news/dr.-eugene-braunwald-world-renowned-cardiologist-to-speak-at-miller-school-. Accessed 30 Aug 2019.
Eugene Braunwauld, MD. Executive committee chair, Heart failure network. Heart failure network. https://hfnetwork.org/about-us/our-leadership/eugene-braunwald-md. Accessed 28 Aug 2019.
Braunwald E, Lambrew CT, Rockoff SD, Ross J Jr, Morrow AG. Idiopathic subaortic stenosis: a description of the disease based upon an analysis of 64 patients. Circulation. 1964;suppl IV:3–119.
Gault JH, Simon AL. Clinical and laboratory findings in patients with nonobstructive intraventricular pressure differences. Circulation. 1970;42(2):235–44.
Hancock EW. Arterial pulse contour in mild muscular subaortic stenosis. Clin Res. 1965;13:91.
White CW, Zimmerman TJ. Prolonged left ventricular ejection time in the post-premature beat: a sensitive sign of idiopathic hypertrophic subaortic stenosis. Circulation. 1975;52(2):306–12.
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Yale, S.H., Tekiner, H., Mazza, J.J., Yale, E.S., Yale, R.C. (2021). Vital Signs. In: Cardiovascular Eponymic Signs. Springer, Cham. https://doi.org/10.1007/978-3-030-67596-7_18
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