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Acute Kidney Injury in Less Well-Resourced Countries

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Pediatric Dialysis

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Abstract

Acute kidney injury (AKI) is a clinical syndrome characterized by rapid decline in renal function resulting in accumulation of nitrogenous waste and disturbed fluid and electrolyte homeostasis. A uniformly accepted definition of AKI based on blood level of creatinine and urine output has helped understand the burden of illness and its impact on outcome. The management of AKI requires knowledge of fluid-electrolyte homeostasis and understanding regarding renal replacement therapy. AKI is associated with short- and long-term complications, and an increased risk of mortality. The clinical syndrome of AKI is the same in less well-resourced countries as in high-income countries (HIC), but AKI etiology and presentation are often different, and management is made more challenging in many settings by the limited available resources. In this chapter, we review the current understanding of the syndrome of AKI in children and focus on the management strategies currently available in less well-resourced countries.

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Authors and Affiliations

  1. Red Cross War Memorial Children’s Hospital, Paediatric Nephrology and Solid Organ Transplant, Rondebosch, Cape Town, South Africa

    Mignon I. McCulloch

  2. All India Institute of Medical Sciences, Department of Pediatrics, New Delhi, India

    Arvind Bagga

Authors
  1. Mignon I. McCulloch
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  2. Arvind Bagga
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Corresponding author

Correspondence to Mignon I. McCulloch .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, University of Missouri-Kansas City, School of Medicine, Division of Pediatric Nephrology, Children’s Mercy Kansas City, Kansas City, MO, USA

    Bradley A. Warady

  2. Stanford University School of Medicine, Division of Pediatric Nephrology, Department of Pediatrics, Palo Alto, CA, USA

    Steven R. Alexander

  3. Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, University of Heidelberg, Heidelberg, Germany

    Franz Schaefer

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McCulloch, M.I., Bagga, A. (2021). Acute Kidney Injury in Less Well-Resourced Countries. In: Warady, B.A., Alexander, S.R., Schaefer, F. (eds) Pediatric Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-030-66861-7_45

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  • DOI: https://doi.org/10.1007/978-3-030-66861-7_45

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-66860-0

  • Online ISBN: 978-3-030-66861-7

  • eBook Packages: MedicineMedicine (R0)

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