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The Elderly Kidney

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Imaging in Nephrology

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Abstract

With advancing age renal function decreases. Estimation of renal function appears necessary to evaluate prognosis, and may be related to glomerular filtration rate (GFR). The physiological aging of the kidney depends on the reduced number of functioning glomeruli and an increased prevalence of nephrosclerosis and with a relative compensatory hypertrophy. These changes may be visible macroscopically with cortical volume reduction and a slight increase in the medulla until the appearance of numerous cystic formations. Ultrasonography is the first-choice technique in the morphological evaluation of the abdominal organs; in fact it can measure the size and volume of the kidney correlating it with renal function in patients with chronic kidney disease.

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References

  1. McClure M, Jorna T, Wilkinson L, Taylor J. Elderly patients with chronic kidney disease: do they really need referral to the nephrology clinic? Clin Kidney J. 2017;10(5):698–702.

    Article  Google Scholar 

  2. Granata A, Fiorini F, D’Amelio A, et al. L’ecocolorDoppler nella pratica clinica nefrologica. Aggiornamenti in Tema Di Nefrologia. 2010;17:192.

    Google Scholar 

  3. McLachlan MS. The ageing kidney. Lancet. 1978;2:143–5.

    Article  CAS  Google Scholar 

  4. Nasr SH, Fidler ME, Valeri AM, Cornell LD, Sethi S, Zoller A, Stokes MB, Markowitz GS, D’Agati VD. Postinfectious glomerulonephritis in the elderly. JASN. 2011;22(1):187–95.

    Article  Google Scholar 

  5. Martin JE, et al. The pathology of ageing: concepts and mechanisms. J Pathol. 2007;211:198–205.

    Article  CAS  Google Scholar 

  6. Macunluoğlu B, Gökçe I, Atakan A, Demirci M, Arı E, Topuzoğlu A, Borazan A. A comparison of different methods for the determination of glomerular filtration rate in elderly patients with chronic renal failure. Int Urol Nephrol. 2011;43(1):257–63.

    Article  Google Scholar 

  7. Cockcroft DW. Gault MH Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31–41.

    Article  CAS  Google Scholar 

  8. Roubenoff R. Sarcopenia: effects on body composition and function. J Gerontol Ser A Biol Sci Med Sci. 2003;58:1012–7.

    Article  Google Scholar 

  9. Bostom AG, et al. Hyperhomocysteinemia in chronic renal disease. JASN. 2002;13:2140–4.

    Article  CAS  Google Scholar 

  10. Quaschning T, et al. Abnormalities in uremic lipoprotein metabolism and its impact on cardiovascular disease. Am J Kidney Dis. 2001;38(4 Suppl 1):S14–9.

    Article  CAS  Google Scholar 

  11. Mancuso D, Comi N, Andreucci M, Donato C, Presta P, Fuiano G. Parametri ecografici renali predittivi di outcome nei pazienti con insufficienza renale cronica. Giornale Italiano di Nefrologia. 2007;24:S-39.

    Google Scholar 

  12. Donadio C, Abdelkawy H, Grassi G. Echographic renal dimensions can predict glomerular filtration rate of potential living kidney donors. Transplant Proc. 2010;42(4):1035–9.

    Article  CAS  Google Scholar 

  13. Afsar B, Elsurer R. Sudden cardiac death and mineral metabolism in chronic kidney disease. Kidney Int. 2010;77(7):648; author reply 648–9

    Article  Google Scholar 

  14. Parenti GC, Basteri V, Bucchi E, Sturani A, Degli Esposti E. Colour-Doppler US evaluation of patients with hypertension and nephropathy. Radiol Med. 2006;111(8):1115–23.

    Article  CAS  Google Scholar 

  15. Parolini C, Noce A, Staffolani E, Giarrizzo GF, Costanzi S, Splendiani G. Renal resistive index and long-term outcome in chronic nephropathies. Radiology. 2009;252(3):888–96.

    Article  Google Scholar 

  16. Tublin ME, Bude RO, Platt JF, et al. The resistive index in renal Doppler sonography: where do we stand? AJR Am J Roentgenol. 2003;180(4):885–92.

    Article  Google Scholar 

  17. Fiorini F, Granata A, Noce A, Durante O, Insalaco M, Di Daniele N. Gli indici di resistenza ecografici in nefrologia: quale significato clinico? G Ital Nefrol. 2013;30(2):1.

    Google Scholar 

  18. Mallappallil M, Friedman EA, Delano BG, McFarlane SI, Salifu MO. Chronic kidney disease in the elderly: evaluation and management. Clin Pract (Lond). 2014;11(5):525–35.

    Article  CAS  Google Scholar 

  19. Chrysochou C, Kalra PA. Epidemiology and natural history of atherosclerotic renovascular disease. Prog Cardiovasc Dis. 2009;52(3):184–95.

    Article  Google Scholar 

  20. Rogowicz-Frontczak A, Araszkiewicz A, Pilacinski S, Zozulinska-Ziolkiewicz D, Wykretowicz A, Wierusz-Wysocka B. Carotid intima-media thickness and arterial stiffness in type 1 diabetic patients are dependent on age and mean blood pressure. Exp Clin Endocrinol Diabetes. 2011;119(5):281–5.

    Article  CAS  Google Scholar 

  21. Romano G, Zanoli L, Romano M, et al. Prevalenza di insufficienza renale occulta e valutazione delle equazioni predittive della VFG in anziani ospedalizzati. Abstract Book XXII. Torino: Congresso Nazionale SIUMB; 2010.

    Google Scholar 

  22. Alicic RZ, Rooney MT, Katherine R. Tuttle diabetic kidney disease, challenges, progress, and possibilities. CJASN. 2017;12(12):2032–45.

    Article  CAS  Google Scholar 

  23. Fuiano G, Caglioti A, Marino F, Mancuso D, Comi N, Natale G, Mangiacapra S, Iodice C. L’insufficienza renale acuta nell’anziano. Giorn It Nefrol. 2001;18:469–81.

    Google Scholar 

  24. Cartabellotta A, Di Iorio B. Diagnosi e valutazione dell’insufficienza renale acuta. Evidence. 2014;6(2):e1000068. https://doi.org/10.4470/E1000068.

    Article  Google Scholar 

  25. Cammarota T, Piccoli G, Sarno A, Rabbia C, Bonenti G. Gilda Olivieri Rene senile: Insufficienza renale nell’anziano. Radiologia geriatrica. Editore: Springer Verlag Anno edizione; 2006. p. 445–59.

    Google Scholar 

  26. Tseng TY, Stoller ML. Obstructive uropathy. Clin Geriatr Med. 2009;25(3):437.

    Article  Google Scholar 

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Authors and Affiliations

  1. Departiment of Radiological Sciences, University La Sapienza of Rome, Rome, Italy

    Francesco M. Drudi

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  1. Francesco M. Drudi
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Correspondence to Francesco M. Drudi .

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Editors and Affiliations

  1. Department of Nephrology and Dialysis, “Cannizzaro” Emergency Hospital, Catania, Italy

    Antonio Granata

  2. Department of Radiology, Cattinara Hospital, University of Trieste, Trieste, Italy

    Michele Bertolotto

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Drudi, F.M. (2021). The Elderly Kidney. In: Granata, A., Bertolotto, M. (eds) Imaging in Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-030-60794-4_12

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  • DOI: https://doi.org/10.1007/978-3-030-60794-4_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-60792-0

  • Online ISBN: 978-3-030-60794-4

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