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Arboviral Central Nervous System Infections

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Neurological Complications of Infectious Diseases

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Arboviruses are transmitted to humans by the bites of infected arthropods, such as mosquitoes and ticks. While most arboviral infections are asymptomatic or result in a non-specific febrile illness, a small proportion cause neuroinvasive disease, presenting most often as meningitis, encephalitis, or myelitis. Some viruses also can cause immune-mediated neurologic complications, such as Guillain-Barré syndrome. Certain viruses and patient characteristics, particularly age and immunosuppression, can lead to greater risk of neuroinvasive disease. The major domestic neurotropic arboviruses are classified in the families Flaviviridae, Peribunyaviridae, and Togaviridae. There are no proven treatments for or licensed vaccines to prevent infections with the domestic arboviruses, and treatment is supportive. Human vaccines are available for a limited number of international neurotropic arboviruses. Prevention of arboviral infection primarily involves using personal protective measures to avoid exposure to the arthropod vectors.

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Authors and Affiliations

  1. Arboviral Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA

    Carolyn Gould & Marc Fischer

Authors
  1. Carolyn Gould
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  2. Marc Fischer
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Correspondence to Carolyn Gould .

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Editors and Affiliations

  1. UT Health McGovern Medical School, Houston, TX, USA

    Rodrigo Hasbun, MD MPH

  2. Div of Infectious Dis, MCN A-2200, Vanderbilt University, Nashville, TN, USA

    Karen C. Bloch, MD MPH

  3. Dept of Infectious Diseases, Apt 635, Cleveland Clinic Foundation, Cleveland, OH, USA

    Adarsh Bhimraj, MD

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Gould, C., Fischer, M. (2021). Arboviral Central Nervous System Infections. In: Hasbun, MD MPH, R., Bloch, MD MPH, K.C., Bhimraj, MD, A. (eds) Neurological Complications of Infectious Diseases. Current Clinical Neurology. Humana, Cham. https://doi.org/10.1007/978-3-030-56084-3_7

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  • DOI: https://doi.org/10.1007/978-3-030-56084-3_7

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-56083-6

  • Online ISBN: 978-3-030-56084-3

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