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Integration of White Matter Tractography in Subcortical and Skull Base Neurosurgical Planning

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Principles of Neuro-Oncology

Abstract

The incorporation of DTI and 3D tractography into the surgical planning workflow has increased awareness of the impact of resection of subcortical pathology as well as extra-axial anterior skull base lesions on the neural network. The 3D perspective that tractography affords in understanding neural anatomy, preoperative planning, and intraoperative navigation has provided unprecedented focus on neural network (both white matter tract and cranial nerve) preservation. The 3D-rendered neural network fused with CTA, structural MRI, and fMRI has prompted reanalysis of both subcortical and skull base surgical algorithms and refinement of conventional surgical approaches. Increased conspicuity of the neural network and integration of tractography in subcortical and skull base surgery aids in corridor choice, intraoperative navigation, and resection with the goal of minimizing the surgical footprint and maximizing patients’ quality of life.

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Authors and Affiliations

  1. Department of Neurosurgery, Aurora Neuroscience Innovation Institute, Aurora St. Luke’s Medical Center, Milwaukee, WI, USA

    Melanie B. Fukui, Alejandro Monroy-Sosa, Srikant S. Chakravarthi, Richard A. Rovin & Austin Epping

  2. Skull Base and Cerebrovascular Laboratory, Advocate Aurora Research Institute, Milwaukee, WI, USA

    Alejandro Monroy-Sosa, Srikant S. Chakravarthi & Austin Epping

  3. Department of Radiology, Aurora St. Luke’s Medical Center, Milwaukee, WI, USA

    Jonathan E. Jennings

  4. Neeka Health, LLC, Los Angeles, CA, USA

    Amin B. Kassam

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  1. Melanie B. Fukui
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  2. Alejandro Monroy-Sosa
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  3. Srikant S. Chakravarthi
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  4. Jonathan E. Jennings
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  5. Richard A. Rovin
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  7. Amin B. Kassam
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Aurora Neuroscience Innovation Institute, Milwaukee, WI, USA

    Alejandro Monroy-Sosa

  2. Department of Neurosurgery, Aurora Neuroscience Innovation Institute, Milwaukee, WI, USA

    Srikant S. Chakravarthi

  3. Instituto Nacional de Cancerología, Mexico City, Mexico

    Jaime G. de la Garza-Salazar

  4. Instituto Nacional de Cancerología, Mexico City, Mexico

    Abelardo Meneses Garcia

  5. Neeka Health, LLC, Milwaukee, WI, USA

    Amin B. Kassam

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Fukui, M.B. et al. (2021). Integration of White Matter Tractography in Subcortical and Skull Base Neurosurgical Planning. In: Monroy-Sosa, A., Chakravarthi, S.S., de la Garza-Salazar, J.G., Meneses Garcia, A., Kassam, A.B. (eds) Principles of Neuro-Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-54879-7_11

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  • DOI: https://doi.org/10.1007/978-3-030-54879-7_11

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