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Myocardial Innervation

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Atlas of Nuclear Cardiology

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Abstract

An important target for cardiac molecular imaging is the autonomic nervous system, which exerts both stimulatory (primarily via sympathetic fibers) and inhibitory (primarily via parasympathetic fibers) effects to adjust cardiac performance to meet varying physiological demands. Neuronal dysregulation is associated with increased risk for adverse outcomes such as heart failure progression and unstable rhythms. In this chapter, advances in radionuclide imaging of the autonomic nervous system using both SPECT and PET tracers are reviewed. The focus is on recent successes in this field and the continuing need to translate these discoveries into guidance for integrating the information into therapeutic decision-making.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Technical University of Munich, Munich, Germany

    Markus Schwaiger

  2. Diagram Consulting, Kihei, HI, USA

    Arnold F. Jacobson

  3. Turku PET Centre, Turku University Hospital and University of Turku, Turko, Finland

    Antti Saraste

  4. Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Jagat Narula

  5. Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany

    Frank M. Bengel

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  1. Markus Schwaiger
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  2. Arnold F. Jacobson
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  3. Antti Saraste
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  4. Jagat Narula
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  5. Frank M. Bengel
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Editors and Affiliations

  1. University of Maryland School of Medicine, Baltimore, MD, USA

    Vasken Dilsizian

  2. Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Jagat Narula

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Schwaiger, M., Jacobson, A.F., Saraste, A., Narula, J., Bengel, F.M. (2021). Myocardial Innervation. In: Dilsizian, V., Narula, J. (eds) Atlas of Nuclear Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-49885-6_11

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