Abstract
Post-operative infectious complications represent a major source of morbidity and mortality for patients undergoing lung resection. Pre-operative antibiotic prophylaxis against wound infection, pneumonia, and empyema are used by many groups with unclear outcomes. Historic trials demonstrated decreased rates of wound infection without consistent improvement in rates of post-operative pneumonia or empyema. Patients undergoing major lung resection, particularly those with planned open operations, should receive pre-operative antibiotic prophylaxis against wound infection. However, the applicability of such trials to thoracoscopic surgery, especially in the era of modern pre-operative antiseptic practices, is questionable. Further prospective data is needed to identify the benefits received by patients undergoing straightforward VATS lung resection at low risk for infectious complications.
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Bryan, D.S., Ferguson, M.K. (2020). Is Antibiotic Prophylaxis Necessary for Major Lung Resection?. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-47404-1_11
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DOI: https://doi.org/10.1007/978-3-030-47404-1_11
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