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Computational Fluid Dynamics in the Arterial System: Implications for Vascular Disease and Treatment

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Mechanisms of Vascular Disease

Abstract

An understanding of the haemodynamics of pulsatile blood flow and the response of the arterial wall to blood pressure in health and disease is vital for those managing vascular disease. Computational Fluid Dynamics (CFD), Finite Element Analysis (FEA) and Fluid-Solid Interaction (FSI) modelling are approaches which can be used to understand the behaviour of blood flow forces and resultant deformation of the arterial wall.

CFD is a flow simulation technique which provides a powerful tool for the study of haemodynamic and image-based modelling of blood flow, using haemodynamic parameters, in the development, diagnosis, and also treatment of cardiovascular disease. The FSI method is helping to make links between blood flow shear stress on arterial wall (WSS) and the distribution of stress into the blood vessel to explain why atherosclerotic plaque develops at arterial junctions for example. These techniques allow engineers and clinicians to study vascular diseases such as atherosclerosis, aneurysm formation and dissection. These techniques are also able to analyse the effects of devices developed to treat vascular disease.

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  • Versteeg HK, Malalasekera W. An introduction to computational fluid dynamics: the finite volume method. Pearson Education; 2007.

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Authors and Affiliations

  1. Faculty of Science and Engineering, WA School of Mines: MECE, Curtin University, Perth, WA, Australia

    Siamak Mishani, Christopher Lagat & Brian Evans

  2. Heart and Vascular Research Institute, Harry Perkins Institute of Medical Research, Medical School, Curtin University, Perth, WA, Australia

    Shirley Jansen

  3. Faculty of Health Sciences, Curtin University, Perth, WA, Australia

    Michael Lawrence-Brown

Authors
  1. Siamak Mishani
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  2. Shirley Jansen
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  3. Michael Lawrence-Brown
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  4. Christopher Lagat
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  5. Brian Evans
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Editors and Affiliations

  1. Discipline of Surgery, The University of Adelaide, Adelaide, SA, Australia

    Robert Fitridge

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Mishani, S., Jansen, S., Lawrence-Brown, M., Lagat, C., Evans, B. (2020). Computational Fluid Dynamics in the Arterial System: Implications for Vascular Disease and Treatment. In: Fitridge, R. (eds) Mechanisms of Vascular Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-43683-4_8

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  • DOI: https://doi.org/10.1007/978-3-030-43683-4_8

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