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The Heart and Vasculature in Turner Syndrome: Development, Surveillance, and Management

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Turner Syndrome

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Abstract

Cardiovascular disease is the leading cause of early morbidity and mortality in girls and women with Turner syndrome (TS). Congenital heart abnormalities are common and often include left-sided obstructive lesions of varying severity. Progressive aortic enlargement may lead to aneurysm formation, dissection, and rupture, a potentially fatal complication. Coronary artery disease, myocardial infarction, and stroke are important acquired cardiovascular complications, which may be further aggravated by an increased propensity for additional comorbidities, such as hypertension, dyslipidemia, diabetes, and obesity. Given the broad spectrum of cardiovascular concerns affecting individuals with Turner syndrome, these patients require a continuum of care, counseling, and preventive management into their adult years. It is therefore particularly relevant that the primary care provider has a good understanding of potential risks involved and how to manage them in order to deliver the best care for these patients and assure their best long-term outcomes.

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  1. Seattle Children’s Hospital/University of Washington, Division of Cardiology, Seattle, WA, USA

    Luciana T. Young

  2. Doernbecher Children’s Hospital, Oregon Health & Sciences University, Portland, OR, USA

    Michael Silberbach

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  1. Division of Endocrinology, Seattle Children’s Hospital, University of Washington, Seattle, WA, USA

    Patricia Y. Fechner

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Young, L.T., Silberbach, M. (2020). The Heart and Vasculature in Turner Syndrome: Development, Surveillance, and Management. In: Fechner, P. (eds) Turner Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-030-34150-3_6

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