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Joint Multi-anatomy Training of a Variational Network for Reconstruction of Accelerated Magnetic Resonance Image Acquisitions

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Machine Learning for Medical Image Reconstruction (MLMIR 2019)

Abstract

Magnetic resonance imaging is a leading image modality for many clinical applications; however, a significant drawback is the lengthy data acquisition. This motivates the development of methods for reconstruction of sparsely sampled image data. One such technique is the Variational Network (VN), a machine learning method that generalizes traditional iterative reconstruction techniques, learning the regularization term from large amounts of image data. Previously, with the VN technique, reconstruction of 4-fold accelerated knee images was shown to be highly successful. In this work we extend the VN approach to applications beyond knee imaging and evaluate the classic VN and a newly developed Unet-VN in 5 different anatomical regions. We evaluate the networks trained individually for each anatomical area as well as jointly trained with data from all anatomical areas. The VN and Unet-VN were trained to reconstruct 4-fold accelerated images of knees, brains, hips, ankles and shoulders. SSIM was calculated to quantitatively evaluate the reconstructed images. Results show that the Unet-VN outperforms the classic VN, both quantitatively – in terms of structural similarity – and qualitatively. The networks jointly trained with multi-anatomy data approach the performance of the individually trained networks and offer the simplicity of a single network for a range of clinical applications which has substantial benefit for clinical translation.

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References

  1. Griswold, M.A., et al.: Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn. Reson. Med. 47(6), 1202–1210 (2002)

    Article  Google Scholar 

  2. Pruessmann, K.P., et al.: SENSE: sensitivity encoding for fast MRI. Magn. Reson. Med. 42(5), 952–962 (1999)

    Article  Google Scholar 

  3. Sodickson, D.K., Manning, W.J.: Simultaneous acquisition of spatial harmonics (SMASH): fast imaging with radiofrequency coil arrays. Magn. Reson. Med. 38(4), 591–603 (1997)

    Article  Google Scholar 

  4. Lustig, M., Donoho, D., Pauly, J.M.: Sparse MRI: the application of compressed sensing for rapid MR imaging. Magn. Reson. Med. 58(6), 1182–1195 (2007)

    Article  Google Scholar 

  5. Aggarwal, H.K., Mani, M.P., Jacob, M.: MoDL: model-based deep learning architecture for inverse problems. IEEE Trans. Med. Imaging 38(2), 394–405 (2019)

    Article  Google Scholar 

  6. Akcakaya, M., et al.: Scan-specific robust artificial-neural-networks for k-space interpolation (RAKI) reconstruction: database-free deep learning for fast imaging. Magn. Reson. Med. 81(1), 439–453 (2019)

    Article  Google Scholar 

  7. Hammernik, K., et al.: Learning a variational network for reconstruction of accelerated MRI data. Magn. Reson. Med. 79(6), 3055–3071 (2018)

    Article  Google Scholar 

  8. Yang, G., et al.: DAGAN: deep de-aliasing generative adversarial networks for fast compressed sensing MRI reconstruction. IEEE Trans. Med. Imaging 37(6), 1310–1321 (2018)

    Article  MathSciNet  Google Scholar 

  9. Zhu, B., et al.: Image reconstruction by domain-transform manifold learning. Nature 555(7697), 487–492 (2018)

    Article  Google Scholar 

  10. Knoll, F., et al.: Assessment of the generalization of learned image reconstruction and the potential for transfer learning. Magn. Reson. Med. 81(1), 116–128 (2019)

    Article  Google Scholar 

  11. Chen, F., et al.: Variable-density single-shot fast spin-echo MRI with deep learning reconstruction by using variational networks. https://doi.org/10.1148/radiol.2018180445

    Article  Google Scholar 

  12. Uecker, M., et al.: ESPIRiT—an eigenvalue approach to autocalibrating parallel MRI: where SENSE meets GRAPPA. Magn. Reson. Med. 71(3), 990–1001 (2014)

    Article  Google Scholar 

  13. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, William M., Frangi, Alejandro F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  14. Pock, T., Sabach, S.: Inertial proximal alternating linearized minimization (iPALM) for nonconvex and nonsmooth problems. SIAM J. Imaging Sci. 9, 1756–1787 (2016)

    Article  MathSciNet  Google Scholar 

  15. Kingma, D.P., Ba, J.: Adam: A Method for Stochastic Optimization. arXiv:1412.6980 (2014)

  16. Knoll, F., et al.: Second order total generalized variation (TGV) for MRI. Magn. Reson. Med. 65(2), 480–491 (2011)

    Article  Google Scholar 

  17. Wang, Z., et al.: Image quality assessment: from error visibility to structural similarity. IEEE Trans. Image Process. 13(4), 600–612 (2004)

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by the US National Institute of Health under grants NIH/NIBIB R01EB024532 and P41EB017183 and the European Research Council starting grant HOMOVIS, No. 640156.

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Correspondence to Patricia M. Johnson .

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Johnson, P.M. et al. (2019). Joint Multi-anatomy Training of a Variational Network for Reconstruction of Accelerated Magnetic Resonance Image Acquisitions. In: Knoll, F., Maier, A., Rueckert, D., Ye, J. (eds) Machine Learning for Medical Image Reconstruction. MLMIR 2019. Lecture Notes in Computer Science(), vol 11905. Springer, Cham. https://doi.org/10.1007/978-3-030-33843-5_7

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  • DOI: https://doi.org/10.1007/978-3-030-33843-5_7

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