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Nutritional Lipidomics in Alzheimer’s Disease

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GeNeDis 2018

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1195))

Abstract

Lipids constitute almost 60% of the brain’s dry weight, and they are thought to be involved in inflammation, neurotransmission and synaptic plasticity. The brain mostly contains sphingolipids, glycerophospholipids and cholesterol which are abundant in myelin and neuronal membranes. The recent rise of the promising area of lipidomic data can be used as a diagnosing tool at the early stages of Alzheimer’s disease allowing novel therapeutic targets. In this review, altered lipid metabolites as well as the impact of diet in the progress of Alzheimer’s disease (AD) are analyzed.

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Authors and Affiliations

  1. Department of Informatics Ionian University, Bioinformatics and Human Electrophysiology Lab (BiHeLab), Corfu, Greece

    Efstathia Kalli

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  1. Efstathia Kalli
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Correspondence to Efstathia Kalli .

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  1. Department of Informatics, Ionian University, Corfu, Greece

    Panayiotis Vlamos

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Kalli, E. (2020). Nutritional Lipidomics in Alzheimer’s Disease. In: Vlamos, P. (eds) GeNeDis 2018. Advances in Experimental Medicine and Biology, vol 1195. Springer, Cham. https://doi.org/10.1007/978-3-030-32633-3_14

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