Abstract
The case illustrates a more rare, but likely under-recognized cause of bradycardia: sinus node dysfunction due to underlying hereditary hemochromatosis. A significant pause from sinus node dysfunction led to infrequent episodes of syncope. The patient’s past medical and family history allow us to discuss a broad differential diagnosis for syncope, and consider diagnostic testing that may help elucidate the cause.
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References
Rautaharju PM, Surawicz B, Gettes LS. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval. J Am Coll Cardiol. 2009;53(11):982–91.
Tester DJ, Ackerman MJ. Genetics of long QT syndrome. Methodist Debakey Cardiovasc J. 2014;10(1):29–33.
Shizukuda Y, Tripodi DJ, Zalos G, Bolan CD, Yau YY, Leitman SF, Waclawiw MA, Rosing DR. Incidence of cardiac arrhythmias in asymptomatic hereditary hemochromatosis subjects with C282Y homozygosity. Am J Cardiol. 2012;109(6):856–60.
Rosengvist M, Hultcrantz R. Prevalence of a haemochromatosis among men with clinical significant bradyarrhythmias. Eur Heart J. 1989;10(5):473–8.
Wang T-L, Chen W-J, Liau C-S, Lee Y-T. Sick sinus syndrome as the early manifestation of cardiac hemochromatosis. J Electrophysiol. 1994;27(1):91–6.
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Tumolo, A.Z. (2020). Taking a Pause to Consider Arrhythmic Etiologies of Syncope. In: Natale, A., Wang, P., Al-Ahmad, A., Estes, N. (eds) Cardiac Electrophysiology. Springer, Cham. https://doi.org/10.1007/978-3-030-28533-3_13
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DOI: https://doi.org/10.1007/978-3-030-28533-3_13
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