Skip to main content

Introduction to PASE Synthesis

  • Chapter
  • First Online:
Pot, Atom, and Step Economy (PASE) Synthesis

Part of the book series: SpringerBriefs in Molecular Science ((GREENCHEMIST))

Abstract

The efficiency of organic synthesis is one of the key aspects of green chemistry. Pot, atom, and step economy (PASE) synthesis is an important tool for achieving high synthetic efficiency. Three kinds of PASE methods including one-pot reactions, cascade reactions, and multicomponent reactions are defined in this chapter. Their differences in operation and reaction process are clarified.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Anastas PT, Warner J (1998) Green chemistry: theory and practice. Oxford University Press, Oxford

    Google Scholar 

  2. Zhang W, Cue BW (eds) (2018) Green techniques for organic synthesis and medicinal chemistry, 2nd edn. Wiley, Chichester

    Google Scholar 

  3. Clarke PA, Santos S, Martin WHC (2007) Green Chem 9:438–440

    Article  CAS  Google Scholar 

  4. Lapkin A, Constable D (eds) (2008) Green chemistry metrics. Measuring and monitoring sustainable processes. Wiley, Hoboken

    Google Scholar 

  5. Dicks AP, Hent A (2015) Green chemistry metrics metrics—a guide to determining and evaluating process greenness. Springer, Heidelberg

    Google Scholar 

  6. Muthengi A, Zhang X, Dhawan G, Zhang W, Corsini F, Zhang W (2018) Green Chem 20:3134–3139

    Article  CAS  Google Scholar 

  7. Muthengi A, Erickson, Muriph RE, Zhang W (2019) J Org Chem 84:5927–5935

    Google Scholar 

  8. Zhang X, Qiu W, Evans J, Kaur M, Jasinski JP, Zhang W (2019) Green Chem 21:2176–2179

    Google Scholar 

  9. Tietze LF, Brasche G, Gericke KM (2006) Domino reactions in organic synthesis. Wiley-VCH, Weinheim

    Book  Google Scholar 

  10. Snyder SA (ed) (2016) Science of synthesis: applications of domino transformations in organic synthesis 1 & 2. Thieme, Stuttgart

    Google Scholar 

  11. Pellisser H (2013) Asymmetric domino reactions. The Royal Society of Chemistry, Cambridge

    Google Scholar 

  12. Zhu J, Bienayme H (eds) (2005) Multicomponent reactions. Wiley-VCH, Weinheim

    Google Scholar 

  13. Zhu J, Wang Q, Wang M-X (2015) Multicomponent reactions in organic synthesis. Wiley-VCH, Weinheim

    Google Scholar 

  14. Herrera RP, Marques-Lopez E (eds) (2015) Multicomponent reactions—concepts and applications for design and synthesis. Wiley, Hoboken

    Google Scholar 

  15. Ameta KL, Dandia A (2017) Multicomponent reactions—synthesis of bioactive heterocycles. CRC Press, London

    Book  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Wei Zhang .

Rights and permissions

Reprints and permissions

Copyright information

© 2019 The Author(s), under exclusive licence to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Zhang, W., Yi, WB. (2019). Introduction to PASE Synthesis. In: Pot, Atom, and Step Economy (PASE) Synthesis. SpringerBriefs in Molecular Science(). Springer, Cham. https://doi.org/10.1007/978-3-030-22596-4_1

Download citation

Publish with us

Policies and ethics