Abstract
We start by recalling some facts from previous chapters. There, many examples of exposures have appeared such as genetic disposition, smoking, lack of education, poor hygiene, polluted water, crowded housing, malnutrition, use of contaminated needles by drug addicts, and unprotected sex; many more will be treated in later chapters. They all exist independently of the health system. They belong to the first four categories of risk factors listed in Sect. 1.5, that is genetic factors, environmental factors, life style, and social and economic conditions. The study of such risk factors is called “observational” or “analytic” epidemiology because one observes and analyzes already existing situations; see Sect. 15.3. Normally we are of course interested in the influence of factors that make the risk of disease, death etc. increase when their level increases.
Clinical trials evaluate the normal curative activity of physicians, which consists in trying to cure or to alleviate diseases of individual patients. They also evaluate measures applied to individuals in order to prevent disease or death. Thus the exposure factor to be studied is “treatment”, either curative or preventive.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Krickeberg, K., Van Trong, P., Thi My Hanh, P. (2019). Clinical (Therapeutic) Trials. In: Epidemiology. Statistics for Biology and Health. Springer, Cham. https://doi.org/10.1007/978-3-030-16368-6_18
Download citation
DOI: https://doi.org/10.1007/978-3-030-16368-6_18
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-16367-9
Online ISBN: 978-3-030-16368-6
eBook Packages: Mathematics and StatisticsMathematics and Statistics (R0)