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Abstract

There are three accessory glands of the male genital system: the seminal vesicles, the prostate gland, and the bulbourethral glands. The prostate gland is the largest of these three glands. The prostate gland has both epithelial and stromal components that can be recognized histologically, and the early development of these components is seen during fetal life. Aberrations of the proper development of the prostate gland can be seen in some syndromes, such as androgen insensitivity syndrome, prune belly syndrome, and posterior urethral valves. Therefore, knowledge of the proper development and histological appearance of the prostate gland during fetal life can be useful. This chapter highlights the histological features of the fetal prostate gland at various points in gestation.

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References

  1. Popek EJ, Tyson RW, Miller GJ, Caldwell SA. Prostate development in prune belly syndrome (PBS) and posterior urethral valves (PUV): etiology of PBS—lower urinary tract obstruction or primary mesenchymal defect? Pediatr Pathol. 1991;11:1–29.

    Article  CAS  Google Scholar 

  2. Schoenwolf GC, Larsen WJ. Larsen’s human embryology. 4th ed. Philadelphia: Churchill Livingstone/Elsevier; 2009.

    Google Scholar 

  3. Risbridger GP, Almahbobi GA, Taylor RA. Early prostate development and its association with late-life prostate disease. Cell Tissue Res. 2005;322:173–81.

    Article  CAS  Google Scholar 

  4. Thomson AA, Cunha GR, Marker PC. Prostate development and pathogenesis. Differentiation. 2008;76:559–64.

    Article  CAS  Google Scholar 

  5. Shapiro E, Huang H, McFadden DE, Masch RJ, Ng E, Lepor H, Wu XR. The prostatic utricle is not a Müllerian duct remnant: immunohistochemical evidence for a distinct urogenital sinus origin. J Urol. 2004;172:1753–6; discussion 1756

    Article  Google Scholar 

  6. Wernert N, Kern L, Heitz P, Bonkhoff H, Goebbels R, Seitz G, et al. Morphological and immunohistochemical investigations of the utriculus prostaticus from the fetal period up to adulthood. Prostate. 1990;17:19–30.

    Article  CAS  Google Scholar 

  7. Glenister TW. The development of the utricle and of the so-called “middle” or “median” lobe of the human prostate. J Anat. 1962;96:443–55.

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Valdés-Dapena MA. Histology of the fetus and newborn. Philadelphia: Saunders; 1979.

    Google Scholar 

  9. Xia T, Blackburn WR, Gardner WA Jr. Fetal prostate growth and development. Pediatr Pathol. 1990;10:527–37.

    Article  CAS  Google Scholar 

  10. Fine SW, McKenney JK. Prostate. In: Mills SE, editor. Histology for pathologists. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2012. p. 987–1002.

    Google Scholar 

  11. Jen PY, Dixon JS. Development of peptide-containing nerves in the human fetal prostate gland. J Anat. 1995;187:169–79.

    PubMed  PubMed Central  Google Scholar 

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Correspondence to Linda M. Ernst .

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Ernst, L.M., Ruchelli, E.D., Huff, D.S. (2019). Prostate Gland. In: Ernst, L., Ruchelli, E., Carreon, C., Huff, D. (eds) Color Atlas of Human Fetal and Neonatal Histology. Springer, Cham. https://doi.org/10.1007/978-3-030-11425-1_14

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  • DOI: https://doi.org/10.1007/978-3-030-11425-1_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11424-4

  • Online ISBN: 978-3-030-11425-1

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