Résumé
L’hypomélanose de Ito (HI) est une génodermatose caractérisée par des alternances de bandes cutanées hypo- et normopigmentées, suivant les lignes de Blaschko, uni- ou bilatérales, apparaissant en général les premières années de vie. Son incidence est estimée entre 1/8 000 et 1/10 000. Le sex-ratio est variable selon les études, mais semble équilibré. Les lésions dermatologiques peuvent être isolées ou associées, dans 75% des cas environ, à des manifestations neurologiques, oculaires et musculosquelettiques. Les anomalies neurologiques sont les plus fréquentes et sont en rapport avec des troubles de lamigration neuronale.
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Lacour, JP. (2012). Hypomélanose de Ito et mosaïcismes pigmentaires. In: Manifestations dermatologiques des maladies d’organes. Springer, Paris. https://doi.org/10.1007/978-2-287-72073-4_23
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DOI: https://doi.org/10.1007/978-2-287-72073-4_23
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