Skip to main content

Health and Economic Consequences of Mucositis

  • Chapter
Oral Mucositis

Abstract

Pain is the most universal symptom associated with mucositis. Numerous studies have documented its relationship to clinically assessed mucositis severity, although the variability of scoring criteria has resulted in some scales having more concordance with patient-reported pain than others. Nonetheless, data supporting a strong association between the course of clinically reported mucositis and the level of patient-reported pain are compelling. For example, Figure 4.1 shows the correlation between mucositis severity as graded by National Cancer Institute Common Toxicity Criteria (NCI-CTC), patient-reported mouth pain, and dysphagia as reported by Cella and colleagues in a study of 323 patients receiving stomatotoxic chemotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 49.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wong PC, Dodd MJ, Miaskowski C, et al. Mucositis pain induced by radiation therapy: prevalence, severity, and use of self-care behaviors. J Pain Symptom Manage. 2006;32:27-37.

    Google Scholar 

  2. Cella D, Pulliam J, Fuchs H, et al. Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy. Cancer. 2003;98:406-412.

    Google Scholar 

  3. Elting LS, Keefe DM, Sonis ST, et al. Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer. 2008;113:2704-2713.

    Google Scholar 

  4. Vera-Llonch M, Oster G, Hagiwara M, Sonis S. Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma. Cancer. 2006;106:329-336.

    Google Scholar 

  5. Nonzee NJ, Dandade NA, Patel U, et al. Evaluating the supportive care costs of severe radiochemotherapy-induced mucositis and pharyngitis: results from a Northwestern

    Google Scholar 

  6. University Costs of Cancer Program pilot study with head and neck and nonsmall cell lung cancer patients who received care at a county hospital, a Veterans Administration hospital, or a comprehensive cancer care center. Cancer. 2008;113:1446-1452.

    Google Scholar 

  7. Sonis ST, Oster G, Fuchs H, et al. Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol. 2001;19:2201-2205.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Healthcare

About this chapter

Cite this chapter

Sonis, S.T. (2012). Health and Economic Consequences of Mucositis. In: Oral Mucositis. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-907673-46-7_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-907673-46-7_4

  • Publisher Name: Springer Healthcare, Tarporley

  • Print ISBN: 978-1-908517-63-0

  • Online ISBN: 978-1-907673-46-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics