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Restrictive Cardiomyopathy

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Clinical Cardiogenetics

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Abstract

Restrictive cardiomyopathy (RCM) is a rare disease, characterized by increased stiffness of the ventricular walls, which causes heart failure because of impaired diastolic filling. In the early stages, systolic function may be normal, but when the disease progresses, systolic function usually declines as well. There is an overlap with other types of cardiomyopathy, such as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and left ventricular noncompaction. Indeed, an autosomal dominantly segregating cardiomyopathy has been described where a single sarcomere gene mutation caused idiopathic RCM in some and HCM in other family members. 1

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Authors and Affiliations

  1. Department of cardiology, University Medical Centre, Utrecht, The Netherlands

    J. H. Kirkels

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  1. J. H. Kirkels
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  2. N. de Jonge
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Correspondence to J. H. Kirkels .

Editor information

Editors and Affiliations

  1. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    H.F. Baars

  2. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    P.A.F.M. Doevendans

  3. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    J.J. van der Smagt

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© 2011 Springer-Verlag London Limited

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Kirkels, J.H., de Jonge, N. (2011). Restrictive Cardiomyopathy. In: Baars, H., Doevendans, P., van der Smagt, J. (eds) Clinical Cardiogenetics. Springer, London. https://doi.org/10.1007/978-1-84996-471-5_8

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  • DOI: https://doi.org/10.1007/978-1-84996-471-5_8

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  • Print ISBN: 978-1-84996-470-8

  • Online ISBN: 978-1-84996-471-5

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