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Umbilical Cord and Its Blood: A Perspective on Its Current and Potential Use in Ophthalmology

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Regenerative Medicine Using Pregnancy-Specific Biological Substances

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Abstract

Recently, umbilical cord blood has been used in the treatment of various ocular surface diseases in ophthalmology. Umbilical cord blood contains essential tear components, growth factors, and neurotrophic factors such as epidermal growth factor, vitamin A, transforming growth factor-b, substance P, insulin-like growth factor, and nerve growth factor. Umbilical cord serum can provide basic nutrients for epithelial renewal and facilitate the proliferation, migration, and differentiation of the ocular surface epithelium. Serum eye drops made from umbilical cord blood can be used safely and effectively for the treatment of severe dry eye with or without Sjögren’s syndrome, ocular complications in graft-versus-host disease, persistent epithelial defects, and neurotrophic keratopathy.

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Authors and Affiliations

  1. Department of Ophthalmology, Chonnam National University Medical School and Hospital, 8 Hak-Dong, Dong-Gu, Gwang-Ju, 501-757, South Korea

    Kyung-Chul Yoon

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  1. Kyung-Chul Yoon
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Correspondence to Kyung-Chul Yoon .

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Editors and Affiliations

  1. Advanced Medical Research Inst., B.P.Poddar Hospital, Vidyasagar Hospital, Kolkata, India

    Niranjan Bhattacharya

  2. Dept. Obstetrics & Gynaecology, Boston University Medical Centre, E. Concord Street 85, Boston, 02118, Massachusetts, USA

    Phillip Stubblefield

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© 2011 Springer London

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Yoon, KC. (2011). Umbilical Cord and Its Blood: A Perspective on Its Current and Potential Use in Ophthalmology. In: Bhattacharya, N., Stubblefield, P. (eds) Regenerative Medicine Using Pregnancy-Specific Biological Substances. Springer, London. https://doi.org/10.1007/978-1-84882-718-9_18

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  • DOI: https://doi.org/10.1007/978-1-84882-718-9_18

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-717-2

  • Online ISBN: 978-1-84882-718-9

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