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Body Composition

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Medical Imaging in Clinical Trials

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Abstract

Human body composition is generally defined as the proportion of fat (adipose), muscle (parenchymal tissues), and bone (mineral) of the body. Body composition can be an indicator of disease or health. Besides fat, muscle, and bone, body composition can be described with varying levels of complexity. This chapter describes the models used to measure body composition and, because of their importance to clinical trials, goes into detail on the use of three imaging methods: dual-energy X-ray absorptiometry, quantitative computed tomography, and MRI.

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Author information

Authors and Affiliations

  1. Department of Radiology and Biomedical Imaging, University of California at San Francisco, 1 Irving Street, Suite A-C108B, San Francisco, CA, 94146, USA

    John A. Shepherd BS, PhD

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  1. John A. Shepherd BS, PhD
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Correspondence to John A. Shepherd BS, PhD .

Editor information

Editors and Affiliations

  1. Medical Affairs, BioClinica Inc., Newtown, Pennsylvania, USA

    Colin G. Miller

  2. Department of Strategy and Regulatory Affairs, TherapeuticsMD, Boca Raton, Florida, USA

    Joel Krasnow

  3. Dept. of Radiology, Columbia University Medical Center, New York, New York, USA

    Lawrence H. Schwartz

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© 2014 Springer-Verlag London

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Shepherd, J.A. (2014). Body Composition. In: Miller, C., Krasnow, J., Schwartz, L. (eds) Medical Imaging in Clinical Trials. Springer, London. https://doi.org/10.1007/978-1-84882-710-3_12

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  • DOI: https://doi.org/10.1007/978-1-84882-710-3_12

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-709-7

  • Online ISBN: 978-1-84882-710-3

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