Abstract
In recent years, there has been a change in the epidemiological profile of infective endocarditis (IE), with an increase in valvular endocarditis in elderly patients, often as a result of health care–associated procedures, both in patients with native valve disease and patients with prosthetic valves [1–3]. In developed countries, the currently listed predisposing factors for endocarditis are degenerative valve sclerosis, valve prostheses, intravenous drug abuse, and frequent use of invasive procedures [4, 5]. In developing countries, however, where the prevalence of rheumatic fever remains high, rheumatic valvular heart disease represents the main risk factor for IE [6].
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References
Moreillon P, Que YA. Infective endocarditis. Lancet. 2004;363:139–49.
Hoen B, Alla F, Selton-Suty C, Beguinot I, Bouvet A, Briancon S, et al. Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA. 2002;288:75–81.
Hill EE, Herijgers P, Claus P, Vanderschueren S, Herregods MC, Peetermans WE. Infective endocarditis: changing epidemiology and predictors of 6-month mortality: a prospective cohort study. Eur Heart J. 2007;28:196–203.
Friedman ND, Kaye KS, Stout JE, McGarry SA, Trivette SL, Briggs JP, et al. Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med. 2002;137:791–7.
Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Eur Heart J. 2009;30:2369–413.
Nkomo VT. Epidemiology and prevention of valvular heart diseases and infective endocarditis in Africa. Heart. 2007;93:1510–9.
Van der Meer JT, Thompson J, Valkenburg HA, Michel MF. Epidemiology of bacterial endocarditis in The Netherlands. I. Patient characteristics. Arch Intern Med. 1992;152:1863–8.
Hogevik H, Olaison L, Andersson R, Lindberg J, Alestig K. Epidemiologic aspects of infective endocarditis in an urban population. A 5-year prospective study. Medicine (Baltimore). 1995;74:324–39.
Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007;116:1736–54.
Lockhart PB. The risk for endocarditis in dental practice. Periodontol 2000. 2000;23:127–35.
Forner L, Larsen T, Kilian M, Holmstrup P. Incidence of bacteremia after chewing, tooth brushing and scaling in individuals with periodontal inflammation. J Clin Periodontol. 2006;33:401–7.
Roberts GJ. Dentists are innocent! ‘Everyday’ bacteremia is the real culprit: a review and assessment of the evidence that dental surgical procedures are a principal cause of bacterial endocarditis in children. Pediatr Cardiol. 1999;20:317–25.
Faden HS. Letter: dental procedures and bacteremia. Ann Intern Med. 1974;81:274.
Starkebaum M, Durack D, Beeson P. The “incubation period” of subacute bacterial endocarditis. Yale J Biol Med. 1977;50:49–58.
Duval X, Leport C. Prophylaxis of infective endocarditis: current tendencies, continuing controversies. Lancet Infect Dis. 2008;8:225–32.
Agha Z, Lofgren RP, VanRuiswyk JV. Is antibiotic prophylaxis for bacterial endocarditis cost-effective? Med Decis Making. 2005;25:308–20.
Durack DT, Lukes AS, Bright DK. New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. Am J Med. 1994;96:200–9.
Li JS, Sexton DJ, Mick N, Nettles R, Fowler Jr VG, Ryan T, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30:633–8.
Sachdev M, Peterson GE, Jollis JG. Imaging techniques for diagnosis of infective endocarditis. Infect Dis Clin North Am. 2002;16:319–37.
Knudsen JB, Fuursted K, Petersen E, Wierup P, Mølgaard H, Poulsen SH, et al. Failure of clinical features of low probability endocarditis. The early echo remains essential. Scand Cardiovasc J. 2011. doi:10.3109/14017431.563863.
Evangelista A, Gonzalez-Alujas MT. Echocardiography in infective endocarditis. Heart. 2004;90:614–7.
Tornos P, Iung B, Permanyer-Miralda G, Baron G, Delahaye F, Gohlke-Barwolf C, et al. Infective endocarditis in Europe: lessons from the Euro heart survey. Heart. 2005;91:571–5.
Cabell CH, Jollis JG, Peterson GE, Corey GR, Anderson DJ, Sexton DJ, et al. Changing patient characteristics and the effect on mortality in endocarditis. Arch Intern Med. 2002;162:90–4.
Fowler Jr VG, Miro JM, Hoen B, Cabell CH, Abrutyn E, Rubinstein E, et al. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA. 2005;293:3012–21.
Aksoy O, Sexton DJ, Wang A, Pappas PA, Kourany W, Chu V, et al. Early surgery in patients with infective endocarditis: a propensity score analysis. Clin Infect Dis. 2007;44:364–72.
Vikram HR, Buenconsejo J, Hasbun R, Quagliarello VJ. Impact of valve surgery on 6-month mortality in adults with complicated, left-sided native valve endocarditis: a propensity analysis. JAMA. 2003;290:3207–14.
Delahaye F, Celard M, Roth O, de Gevigney G. Indications and optimal timing for surgery in infective endocarditis. Heart. 2004;90:618–20.
Tleyjeh IM, Steckelberg JM, Georgescu G, Ghomrawi HM, Hoskin TL, Enders FB, et al. The association between the timing of valve surgery and six-month mortality in left-sided infective endocarditis. Heart. 2008;94:892–6.
Thuny F, Beurtheret S, Mancini J, Gariboldi V, Casalta JP, Riberi A, et al. The timing of surgery influences mortality and morbidity in adults with severe complicated infective endocarditis: a propensity analysis. Eur Heart J. 2011;32(16):2027–33.
Di Salvo G, Habib G, Pergola V, et al. Echocardiography predicts embolic events in infective endocarditis. J Am Coll Cardiol. 2001;37:1067–76.
Thuny F, Di Salvo G, Belliard O, Avierinos JF, Pergola V, Rosenberg V, et al. Risk of embolism and death in infective endocarditis: prognostic value of echocardiography: a prospective multicenter study. Circulation. 2005;112:69–75.
Heiro M, Nikoskelainen J, Engblom E, et al. Neurologic manifestations of infective endocarditis: a 17-year experience in a teaching hospital in Finland. Arch Intern Med. 2000;160:2781–7.
Dickerman SA, Abrutyn E, Barsic B, Bouza E, Cecchi E, Moreno A, et al. The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS). Am Heart J. 2007;154:1086–94.
Sanfilippo AJ, Picard MH, Newell JB, Rosas E, Davidoff R, Thomas JD, et al. Echocardiographic assessment of patients with infectious endocarditis: prediction of risk for complications. J Am Coll Cardiol. 1991;18:1191–9.
Cabell CH, Pond KK, Peterson GE, Durack DT, Corey GR, Anderson DJ, et al. The risk of stroke and death in patients with aortic and mitral valve endocarditis. Am Heart J. 2001;142:75–80.
Steckelberg JM, Murphy JG, Ballard D, Bailey K, Tajik AJ, Taliercio CP, et al. Emboli in infective endocarditis: the prognostic value of echocardiography. Ann Intern Med. 1991;114:635–40.
Mugge A, Daniel WG, Frank G, Lichtlen PR. Echocardiography in infective endocarditis: reassessment of prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach. J Am Coll Cardiol. 1989;14:631–8.
Vilacosta I, Graupner C, San Roman JA, Sarria C, Ronderos R, Fernandez C, et al. Risk of embolization after institution of antibiotic therapy for infective endocarditis. J Am Coll Cardiol. 2002;39:1489–95.
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Two-dimensional (2D) transthoracic echocardiography (TTE), apical three chambers view. Aortic valve vegetation (see arrow) in a 68-year-old woman (Enterococcus fecalis)
Video 1.AVI (1,391 KB)
2D TTE, parasternal long axis view. Aortic valve vegetation (see arrows) in a 68-year-old woman (Enterococcus fecalis)
Video 2.AVI (1,464 KB)
2D TTE, apical four-chamber view. Aortic valve vegetation in a 68-year-old woman (Enterococcus fecalis)
Video 3.AVI (1,418 KB)
76621_2_En_6_MOESM4_ESM.mpg
2D TTE, parasternal short axis view. Pseudoaneurysm of aortic biological prosthesis, during diastole (a), and during systole (b), see arrows
Video 4.MPG (154 KB)
76621_2_En_6_MOESM5_ESM.mpg
2D TTE, parasternal short axis view. Pseudoaneurysm of aortic biological prosthesis, during diastole (a), and during systole (b), see arrows
Video 5.MPG (202 KB)
76621_2_En_6_MOESM6_ESM.mpg
2D TTE, apical four-chamber view. Pseudoaneurysm of aortic mechanical prosthesis
Video 6.MPG (278 KB)
TEE. Post-infectious fistula on biological aortic prosthesis, clearly visible during diastole (a) and systole (yellow arrows). (b) The green arrow indicates the vegetation attached to the prosthesis. During systole (c and d), two communications between the two neighboring cavities (white arrows) represented by the aortic bulb and the newly formed para-prosthetic cavity
Video 7.MPG (3,178 KB)
TEE. Post-infectious fistula on biological aortic prosthesis, clearly visible during diastole (a) and systole (yellow arrows). (b) The green arrow indicates the vegetation attached to the prosthesis. During systole (c and d), two communications between the two neighboring cavities (white arrows) represented by the aortic bulb and the newly formed para-prosthetic cavity
Video 8.MPG (6,582 KB)
2D TTE, apical three-chamber view with and without color Doppler. Dehiscence and rocking of the aortic biological prosthesis causing para-prosthetic regurgitation
Video 9.wmv (1,378 KB)
2D TTE, apical three-chamber view with and without color Doppler. Dehiscence and rocking of the aortic biological prosthesis causing para-prosthetic regurgitation
Video 10.wmv (1,024 KB)
76621_2_En_6_MOESM11_ESM.mpg
2D TTE, apical two-chamber view. Mitral valvular vegetation (attached to the posterior mitral leaflet) in 42-year-old man with staphylococcal IE at the time of diagnosis (Video 6.11), and after 2 weeks of antibiotic therapy (Video 6.12)
Video 11.MPG (162 KB)
76621_2_En_6_MOESM12_ESM.mpg
Video 12.MPG (220 KB)
76621_2_En_6_MOESM13_ESM.mpg
[2D TTE e 3D TTE]. Mitral valve endocarditis [S. Epidermidis] in a 42 year old man with a large (21 mm) and mobile vegetation adherent to the posterior mitral leaflet; video 13 (3D TTE), Video 14,15 (3D TTE reconstruction from atrial view and ventricular view respectively)
Video 13.AVI (270 KB)
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Video 14 atrial view.AVI (221 KB)
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Video 15 Ventricular view.AVI (224 KB)
Video 6.4
2D TTE, parasternal short axis view. Pseudoaneurysm of aortic biological prosthesis, during diastole (a), and during systole (b), see arrows
Video 4.MPG (154 KB)
Video 6.5
2D TTE, parasternal short axis view. Pseudoaneurysm of aortic biological prosthesis, during diastole (a), and during systole (b), see arrows
Video 5.MPG (202 KB)
Video 6.6
2D TTE, apical four-chamber view. Pseudoaneurysm of aortic mechanical prosthesis
Video 6.MPG (278 KB)
Videos 6.11
2D TTE, apical two-chamber view. Mitral valvular vegetation (attached to the posterior mitral leaflet) in 42-year-old man with staphylococcal IE at the time of diagnosis (Video 6.11), and after 2 weeks of antibiotic therapy (Video 6.12)
Video 11.MPG (162 KB)
Videos 6.12
Video 12.MPG (220 KB)
Videos 6.13
[2D TTE e 3D TTE]. Mitral valve endocarditis [S. Epidermidis] in a 42 year old man with a large (21 mm) and mobile vegetation adherent to the posterior mitral leaflet; video 13 (3D TTE), Video 14,15 (3D TTE reconstruction from atrial view and ventricular view respectively)
Video 13.AVI (270 KB)
Videos 6.14
Video 14 atrial view.AVI (221 KB)
Videos 6.15
Video 15 Ventricular view.AVI (224 KB)
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Lisi, M., Mondillo, S., Galderisi, M. (2012). Infective Endocarditis. In: Henein, M. (eds) Clinical Echocardiography. Springer, London. https://doi.org/10.1007/978-1-84882-521-5_6
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DOI: https://doi.org/10.1007/978-1-84882-521-5_6
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