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Skin and Psoriasis

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Atlas of Psoriatic Arthritis

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Abstract

Psoriasis is a chronic, inflammatory skin disease typically manifesting as well-demarcated plaques with varying degrees of erythema, scale, thickness, and body surface area affected. It is considered a heritable, T-cell-mediated autoimmune disorder. Like many genetic disorders, there is a large range of phenotypic expression, and many environmental factors, such as infection, trauma, drugs, and stress, are believed to influence the onset, course, and severity of psoriasis. Psoriasis can be extremely detrimental to the individual with significant psychosocial and medical implications. The disease is considered moderate to severe in about 30% of patients, and the most effective treatments are immunosuppressive agents and light therapy with risk of end-organ toxicity [1].

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Author information

Authors and Affiliations

  1. Utah Psoriasis Initiative, University of Utah, Salt Lake City, UT, USA

    Kristina P. Callis & Gerald G. Krueger

Authors
  1. Kristina P. Callis
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  2. Gerald G. Krueger
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Editor information

Editors and Affiliations

  1. School of Medicine, University of Washington, Seattle, WA, USA

    P. J. Mease MED (RHUUH)

  2. Academic Unit of Musculoskeletal and Rehabilitation Medicine, University of Leeds, Leeds, UK

    P. S. Helliwell DM, PhD, FRCP

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© 2008 Springer-Verlag London Limited

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Callis, K.P., Krueger, G.G. (2008). Skin and Psoriasis. In: Mease, P.J., Helliwell, P.S. (eds) Atlas of Psoriatic Arthritis. Springer, London. https://doi.org/10.1007/978-1-84628-897-5_5

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  • DOI: https://doi.org/10.1007/978-1-84628-897-5_5

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-896-8

  • Online ISBN: 978-1-84628-897-5

  • eBook Packages: MedicineMedicine (R0)

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