Abstract
Intraoperative irradiation (IORT) refers to delivery of a single dose of irradiation to a surgically exposed tumor or tumor bed while the normal tissues are protected from the irradiation either by retracting the mobilized tissue or by shielding the anatomically fixed tissues. IORT has traditionally been performed by using an electron beam as the source of irradiation.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Nag S, Orton C. Development of intraoperative high dose rate brachytherapy for treatment of resected tumor beds in anesthetized patients. Endcurieth Hyperth Oncol. 1993;9:187–93.
Nag S, Martinez-Monge R, Gupta N. Intraoperative radiation therapy using electron-beam and high-dose-rate brachytherapy. Cancer J. 1997;10:94–101.
Harrison LB, Enker WE, Anderson LL. High dose rate intraoperative radiation therapy for colorectal cancer. Part I. Oncology. 1995;9:679–84.
Nag S, Lukas P, Thomas DS, Harrison L. Intraoperative high dose rate remote brachytherapy. In: Nag S, editor. High dose rate brachytherapy: a textbook. Armonk, NY: Futura Publishing Co.; 1994. p. 427–45.
Lukas P, Stepan R, Ries G, et al. A new modality for intraoperative radiation therapy with a high-dose-rate-afterloading unit. Radiology. 1991;181:251.
McCullough E, Anderson JA. The dosimetric properties of an applicator system for intraoperative electron beam therapy utilizing a Clinic-8 accelerator. Med Phys. 1982;9:261–8.
Gunderson LL, Nelson H, Martenson JA, et al. Locally advanced primary colorectal cancer. Intraoperative electron and external beam irradiation ± 5FU. Int J Radiat Oncol Biol Phys. 1997;37:601–40.
Dritschilo A, Harter KW, Thomas D, et al. Intraoperative radiation therapy of hepatic metastases: technical aspects and report of a pilot study. Int J Radiat Oncol Biol Phys. 1988;14:1007–11.
Thomas DS, Nauta RJ, Rodgers JE, et al. Intraoperative high-dose rate interstitial irradiation of hepatic metastases from colorectal carcinoma. Results of a phase I-II trial. Cancer. 1993;71:1977–81.
Nag S. Radiotherapy and brachytherapy for recurrent colorectal cancer. Semin Surg Oncol. 1991;7:177–80.
Erickson B, Nag S. Bile duct and liver. In: Nag S, editor. Principles and practice of brachytherapy. Armonk, NY: Futura Publishing Co.; 1997. p. 367–91.
Vaidya JS, Baum M, Tobias JS, et al. Targeted intraoperative radiotherapy (TARGIT) yields very low recurrence rates when given as a boost. Int J Radiat Oncol Biol Phys. 2006;66:1335–8.
Schneider F, Fuchs H, Lorenz F, et al. A novel device for intravaginal electronic brachytherapy. Int J Radiat Oncol Biol Phys. 2009;74(4):1298–305.
Dickler A, Ivanov O, Francescatti D. Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing Xoft Axxent electronic brachytherapy. World J Surg Oncol. 2009;7:1–6.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Nag, S., Willett, C.G., Gunderson, L.L., Harrison, L.B., Calvo, F.A., Biggs, P. (2011). IORT with Electron-Beam, High-Dose-Rate Brachytherapy or Low-KV/Electronic Brachytherapy: Methodological Comparisons. In: Gunderson, L., Willett, C., Calvo, F., Harrison, L. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-61779-015-7_6
Download citation
DOI: https://doi.org/10.1007/978-1-61779-015-7_6
Published:
Publisher Name: Humana Press
Print ISBN: 978-1-61779-014-0
Online ISBN: 978-1-61779-015-7
eBook Packages: MedicineMedicine (R0)