Abstract
Gastroparesis refers to delayed stomach emptying in the absence of mechanical obstruction of the gastric outlet. It can be due to failure to generate an aboral pressure gradient within the stomach (i.e., pump failure); inadequate relaxation of the pylorus (i.e., functional obstruction); or an inappropriate pressure gradient between the antrum and the duodenum caused by antral hypomotility or duodenal spasm. The majority of patients with gastroparesis can be categorized as being related to diabetes mellitus (type 1 or type 2), vagus nerve malfunction secondary to primary injury (vagotomy) or secondary injury (antireflux or bariatric surgery, heart-lung transplantation) or as idiopathic. Before classifying gastroparesis as being idiopathic, there are a number of other putative etiologies that must be considered. The other putative etiologies are the subject of this chapter.
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Dadabhai, A., Fisher, R.S. (2012). Gastroparesis from Other Causes. In: Parkman, H., McCallum, R. (eds) Gastroparesis. Clinical Gastroenterology. Humana Press. https://doi.org/10.1007/978-1-60761-552-1_19
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DOI: https://doi.org/10.1007/978-1-60761-552-1_19
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