Abstract
The early chemistry of thiamine deficiency goes back many years. The purpose of this introductory chapter is to review some of the remarkable discoveries relating to thiamine, thiamine-dependent enzymes, the relation to a deficiency of thiamine, and results, which led to the awarding of a Nobel prize to Christiaan Eijkman in 1929 in physiology or medicine for his work involving thiamine.
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Notes
- 1.
It is important to note that Frederick Gowland Hopkins shared the Nobel Prize in Physiology or Medicine with Eijkman in 1929. It was awarded to Hopkins for his work on vitamins and for his finding that muscle contraction leads to lactate accumulation.
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McCandless, D.W. (2010). Early Chemistry. In: Thiamine Deficiency and Associated Clinical Disorders. Contemporary Clinical Neuroscience. Humana Press. https://doi.org/10.1007/978-1-60761-311-4_1
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DOI: https://doi.org/10.1007/978-1-60761-311-4_1
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