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References

  1. Griffiths CE, Barker JN (2007) Pathogenesis and clinical features of psoriasis. Lancet 370:263–271

    Article  PubMed  CAS  Google Scholar 

  2. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB (2006) Risk of myocardial infarction in patients with psoriasis. JAMA 296:1735–1741

    Article  PubMed  CAS  Google Scholar 

  3. Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X et al (2009) The risk of stroke in patients with psoriasis. J Invest Dermatol 129(10):2411–2418

    Article  PubMed  CAS  Google Scholar 

  4. Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaci D et al (2007) Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol 156:271–276

    Article  PubMed  CAS  Google Scholar 

  5. Gisondi P, Fantin F, Del Giglio M, Valbusa F, Marino F, Zamboni M et al (2009) Chronic plaque psoriasis is associated with increased arterial stiffness. Dermatology 218:110–113

    Article  PubMed  Google Scholar 

  6. Ucak S, Ekmekci TR, Basat O, Koslu A, Altuntas Y (2006) Comparison of various insulin sensitivity indices in psoriatic patients and their relationship with type of psoriasis. J Eur Acad Dermatol Venereol 20:517–522

    Article  PubMed  CAS  Google Scholar 

  7. Kaye JA, Li L, Jick SS (2008) Incidence of risk factors for myocardial infarction and other vascular diseases in patients with psoriasis. Br J Dermatol 159:895–902

    Article  PubMed  CAS  Google Scholar 

  8. Cohen AD, Dreiher J, Shapiro Y, Vidavsky L, Vardy DA, Davidovici B et al (2008) Psoriasis and diabetes: a population-based cross-sectional study. J Eur Acad Dermatol Venereol 22:585–589

    Article  PubMed  CAS  Google Scholar 

  9. Wakkee M, Thio HB, Prens EP, Sijbrands EJ, Neumann HA (2007) Unfavorable cardiovascular risk profiles in untreated and treated psoriasis patients. Atherosclerosis 190:1–9

    Article  PubMed  CAS  Google Scholar 

  10. Naldi L, Chatenoud L, Linder D (2005) Belloni Fortina A, Peserico A, Virgili AR, et al. Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study. J Invest Dermatol 125:61–67

    Article  PubMed  CAS  Google Scholar 

  11. Setty AR, Curhan G, Choi HK (2007) Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses’ Health Study II. Arch Intern Med 167:1670–1675

    Article  PubMed  Google Scholar 

  12. Després JP, Lemieux I, Bergeron J et al (2008) Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol 28:1039–1049

    Article  PubMed  Google Scholar 

  13. Gisondi P, Girolomoni G (2009) Psoriasis and atherothrombotic diseases: disease-specific and non-disease-specific risk factors. Semin Thromb Hemost 35:313–324

    Article  PubMed  CAS  Google Scholar 

  14. Dixon WG, Watson KD, Lunt M, Hyrich KL (2007) Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register. Arthritis Rheum 56:2905–2912

    Article  PubMed  CAS  Google Scholar 

  15. Grundy SM, Brewer HB Jr, Cleeman JI, Smith SC Jr, Lenfant C, American Heart Association; National Heart, Lung, and Blood Institute (2004) Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 109:433–438

    Article  PubMed  Google Scholar 

  16. National Institute of Health (2001) Third report of the national Cholesterol Education Program Export Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Executive Summary, National Institute of Health, National Hearth, Lung and Blood Institute, Bethesda, MD (NIH publ no 01-3670)

    Google Scholar 

  17. Gisondi P, Tessari G, Conti A, Piaserico S, Schianchi S, Peserico A et al (2007) Prevalence of metabolic syndrome in patients with psoriasis: a hospital-based case-control study. Br J Dermatol 157:68–73

    Article  PubMed  CAS  Google Scholar 

  18. Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M (2006) Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 298:321–328

    Article  PubMed  Google Scholar 

  19. Gisondi P, Targher G, Zoppini G, Girolomoni G (2009) Non-alcoholic fatty liver disease in patients with chronic plaque psoriasis. J Hepatol 51:758–764

    Article  PubMed  CAS  Google Scholar 

  20. Prodanovich S, Ma F, Taylor JR, Pezon C, Fasihi T, Kirsner RS (2005) Methotrexate reduces incidence of vascular diseases in veterans with psoriasis or rheumatoid arthritis. J Am Acad Dermatol 52:262–267

    Article  PubMed  Google Scholar 

  21. Rosenberg P, Urwitz H, Johannesson A, Ros AM, Lindholm J, Kinnman N et al (2007) Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment. J Hepatol 46:1111–1118

    Article  PubMed  CAS  Google Scholar 

  22. Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB et al (2009) Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol 61:451–485

    Article  PubMed  CAS  Google Scholar 

  23. Vahlquist C, Olsson AG, Lindholm A, Vahlquist A (1995) Effects of gemfibrozil (Lopid) on hyperlipidemia in acitretin-treated patients. Results of a double-blind cross-over study. Acta Derm Venereol 75:377–380

    PubMed  CAS  Google Scholar 

  24. Antoniou C, Dessinioti C, Katsambas A, Stratigos AJ (2007) Elevated triglyceride and cholesterol levels after intravenous antitumour necrosis factor-alpha therapy in a patient with psoriatic arthritis and psoriasis vulgaris. Br J Dermatol 156:1090–1091

    Article  PubMed  CAS  Google Scholar 

  25. Stinco G, Piccirillo F, Patrone P (2007) Hypertriglyceridaemia during treatment with adalimumab in psoriatic arthritis. Br J Dermatol 157:1273–1274

    Article  PubMed  CAS  Google Scholar 

  26. Dominique L (2008) Liver toxicity of TNFalpha antagonists. Joint Bone Spine 75:636–638

    Article  PubMed  Google Scholar 

  27. Gisondi P, Cotena C, Tessari G, Girolomoni G (2008) Anti-tumour necrosis factor-alpha therapy increases body weight in patients with chronic plaque psoriasis: a retrospective cohort study. J Eur Acad Dermatol Venereol 22:341–344

    Article  PubMed  CAS  Google Scholar 

  28. Saraceno R, Schipani C, Mazzotta A, Esposito M, Di Renzo L, De Lorenzo A et al (2008) Effect of anti-tumor necrosis factor-alpha therapies on body mass index in patients with psoriasis. Pharmacol Res 57:290–295

    Article  PubMed  CAS  Google Scholar 

  29. Franchimont D, Roland S, Gustot T, Quertinmont E, Toubouti Y, Gervy MC et al (2005) Impact of infliximab on serum leptin levels in patients with Crohn’s disease. J Clin Endocrinol Metab 90:3510–3516

    Article  PubMed  CAS  Google Scholar 

  30. Gisondi P, Del Giglio M, Di Francesco V, Zamboni M, Girolomoni G (2008) Weight loss makes obese patients with moderate to severe chronic plaque psoriasis highly responsive to low dose cyclosporine: a randomized, controlled, investigator blinded, clinical trial. Am J Clin Nutr 88:1242–1247

    PubMed  CAS  Google Scholar 

  31. Dixon WG, Watson KD, Lunt M, Hyrich KL, Silman AJ, Symmons D, British Society for Rheumatology Biologics Register Control Centre Consortium, British Society for Rheumatology Biologics Register (2007) Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register. Arthritis Rheum 56:2905–2912

    Article  PubMed  CAS  Google Scholar 

  32. Bosello S, Santoliquido A, Zoli A, Di Campli C, Flore R, Tondi P et al (2008) TNF-alpha blockade induces a reversible but transient effect on endothelial dysfunction in patients with long-standing severe rheumatoid arthritis. Clin Rheumatol 27:833–839

    Article  PubMed  Google Scholar 

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Gisondi, P., Girolomoni, G. (2010). Metabolic Syndrome in Psoriasis. In: Smoller, B., Rongioletti, F. (eds) Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-60761-181-3_12

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