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Mast Cell Activation and the Role of Eicosanoids

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Guide to Signal Pathways in Immune Cells

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Abstract

Mast cells trigger allergic and other immune reactions. Details of their signal transduction pathways leading to discharge of cellular granules are given. Control is exerted also by eicosanoids generated by activation of cell phospholipase A2, by cyclic adenosine monophosphate (AMP) and by nitric oxide.

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Authors and Affiliations

  1. The Royal Society of Medicine, London, W1G 0AE, United Kingdom

    E. Nigel Wardle

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  1. E. Nigel Wardle
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Correspondence to E. Nigel Wardle .

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Wardle, E.N. (2009). Mast Cell Activation and the Role of Eicosanoids. In: Guide to Signal Pathways in Immune Cells. Humana Press. https://doi.org/10.1007/978-1-60327-538-5_6

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