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Molecular Targets in Renal Tumors: Pathologic Assessment

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Renal Cell Carcinoma

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Abstract

Pathologists play critical roles in the clinical management and research of renal cell carcinoma (RCC). Careful assessment by pathologists of a cancer-harboring kidney specimen not only renders an accurate histological diagnosis and classification, but also provides information important for prognosis and therapeutic decisions. In addition, redundant tumor tissues not required for diagnosis could be procured for clinical trials, experimental therapies, and research. This chapter briefly describes how the RCC specimens are processed in pathology laboratories and how clinicians can facilitate such a process. In addition, important pathological and cytogenetic features of different subtypes of RCC will also be discussed.

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Author information

Authors and Affiliations

  1. Tissue Microarray Core, Departments of Anatomic Pathology and Cancer Biology, Glickman Urological Institute, Cleveland, OH

    M. Zhou

Authors
  1. M. Zhou
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Editor information

Editors and Affiliations

  1. Cleveland Clinic Foundation, Cleveland Clinic Taussig Cancer Center and CCF Lerner College of Medicine of CWRU, Cleveland, OH

    Ronald M. Bukowski

  2. Division of Medical Oncology & Experimental Therapeutics, City of Hope National Medical, Center/Beckman Research Institute, Duarte, CA

    Robert A. Figlin

  3. Memorial-Sloan Kettering Cancer Center, New York, NY

    Robert J. Motzer

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Zhou, M. (2009). Molecular Targets in Renal Tumors: Pathologic Assessment. In: Bukowski, R.M., Figlin, R.A., Motzer, R.J. (eds) Renal Cell Carcinoma. Humana Press. https://doi.org/10.1007/978-1-59745-332-5_3

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  • DOI: https://doi.org/10.1007/978-1-59745-332-5_3

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-737-2

  • Online ISBN: 978-1-59745-332-5

  • eBook Packages: MedicineMedicine (R0)

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