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Topical Therapy

Iontophoresis and Electromotive Drug Administration

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Peyronie’S Disease

Abstract

Electromotive drug administration (EMDA) is a method of increasing the transport of drugs across barriers by means of an electric current. In patients with Peyronie’s disease, EMDA of verapamil into the tunica albuginea provides measurable drug levels in plaque tissue. Four clinical studies using different methods showed that EMDA of verapamil and dexamethasone is a safe and effective treatment for Peyronie’s disease, reducing plaque volume, penile deviation, and pain, and can contribute to the improvement in erectile capacity and sexual function.

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© 2007 Humana Press Inc., Totowa, NJ

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Di Stasi, S.M. et al. (2007). Topical Therapy. In: Levine, L.A. (eds) Peyronie’S Disease. Current Clinical Urology. Humana Press. https://doi.org/10.1007/978-1-59745-161-1_8

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  • DOI: https://doi.org/10.1007/978-1-59745-161-1_8

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-614-6

  • Online ISBN: 978-1-59745-161-1

  • eBook Packages: MedicineMedicine (R0)

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