Abstract
Neurologic tests can establish a diagnosis when several possible diagnoses exist, help make therapeutic decisions, and assess the results of treatment. These tests are divided into the evaluation of (a) function, (b) structure, and (c) underlying molecular/genetic abnormalities. Tests to evaluate function include the neurologic exam, neuropsychological tests, electroencephalogram, electromyogram, and nerve conduction tests. Tests to evaluate nervous system structure include lumbar puncture and cerebrospinal fluid examination, neuroimaging, single photon/positron emission computed tomography (SPECT or PET), and finally, to assess underlying genetic abnormalities, specialized genetic tests are indicated. Each of these neurologic tests is discussed in terms of their basic principles, indications, cost, and possible side effects.
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Recommended Reading
Fishman RA. Cerebrospinal fluid in diseases of the nervous system. 2nd edn. Philadelphia: WB Saunders; 1992. (Excellent compendium of normal CSF values and changes that occur in many diseases)
Biskup S, Gasser T. Genetic testing in neurological diseases. J Neurol. 2012;259:1249–54. (Nice general review of the types of genetic disorders seen in neurologic diseases and current testing to detect them)
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Davis, L., Pirio Richardson, S. (2015). Common Neurologic Tests. In: Fundamentals of Neurologic Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2359-5_3
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DOI: https://doi.org/10.1007/978-1-4939-2359-5_3
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Publisher Name: Springer, New York, NY
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