Abstract
A number of unique features distinguish hypertension in Blacks from other populations, and attempts to address these features have been incorporated into multiple national and international guidelines. Although there remains a significant lack of data, over the past decade several clinical outcome trials with sufficient sample size of Blacks have been completed. The results of these trials have informed these guideline recommendations and resulted in several common themes. However, differences in the interpretation of the trial results as well as differences in the methodology used to develop the guidelines have led to significant differences in recommendations. The objective of this chapter is to compare both the recommendations and the evidence base and rationale forming the basis for current recommendations for the treatment of hypertension in Black-hypertensive populations. Guidelines selected for review are those that specifically indicate recommendations in Black populations or that reviewed studies conducted in Black-hypertensive patients though not specifically making recommendations by race. In patients requiring the use of BP lowering medications for concomitant disorders (e.g., coronary heart disease, heart failure, proteinuric chronic kidney disease) in addition to treating hypertension, the focus of the chapter will be on recommendations for lowering elevated blood pressure assuming the addition of the agents specifically indicated for the treatment of non-blood pressure-related disorders.
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Thornton, G., Wright, J.T. (2015). New Guideline Recommendations on Hypertension: Preventing CVD and Renal Disease with Applications to Blacks. In: Ferdinand, K. (eds) Hypertension in High Risk African Americans. Clinical Hypertension and Vascular Diseases. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2010-5_16
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DOI: https://doi.org/10.1007/978-1-4939-2010-5_16
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