Abstract
Endoscopic therapies targeting pancreatic neuroendocrine tumors (PNETs) are not considered standard of care. This is especially true for patients with localized and potentially curable disease. On the other hand, endoscopic guided therapies, to debulk the tumor and/or to control symptoms, have been offered to patients with either metastatic disease or those who are poor surgical candidates. Various endoscopic ultrasound (EUS)-guided local ablation therapies such as radiofrequency ablation, photodynamic therapy, and brachytherapy are some of the other modalities that have been evaluated or are under investigation for the treatment of PNETs. EUS has also been used to deliver fiducials within or adjacent to small PNETs to facilitate visualization of these small lesions at the time of parenchymal-sparing pancreatic surgery.
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Raina, A., Chandrasekhara, V. (2015). Endoscopic Approaches to Treatment of Pancreatic Neuroendocrine Neoplasms. In: Pisegna, J. (eds) Management of Pancreatic Neuroendocrine Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1798-3_8
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