Abstract
Schwann cells play a very important role in the many aspects of the peripheral nervous system. Schwann cells have well-developed cellular processes which allow to wrap around axons and form tight junctions with each other [1–3]. Each axon is sheathed by one layer of Schwann cells which connect to each other at the node of Ranvier. This wrapping property might underlie the wavy appearance of nuclei seen in nerve sheath tumors. If one visions the Schwann cell arrangement in a nerve fascicle, the resemblance to the Verocay body characteristic of schwannomas becomes evident. Apparently, the neoplastic cells are polarized and supported by basal laminin on both sides.
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Sun, X. (2015). Nervous System. In: Well-Differentiated Malignancies. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1692-4_4
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DOI: https://doi.org/10.1007/978-1-4939-1692-4_4
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