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Cutaneous Tissue

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Well-Differentiated Malignancies

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

The important barrier function of the epidermis is supported by the epidermal appendages such as the hair follicles and sebaceous and sweat glands. The epidermis contains a basal layer of proliferative keratinocytes that adhere to the underlying basement membrane. In the process of differentiation, the committed basal cells detach from the basement membrane and progress through different stages and form three distinctive layers: the spinous, the granular, and the stratum corneum. The molecular mechanism underlying this complex process is still poorly understood [1, 2].

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Authors and Affiliations

  1. Department of Pathology Beckley Veterans Medical Center (West Virginia), McGuire Veterans Medical Center, Virginia Commonwealth University, Richmond, VA, USA

    Xichun Sun M.D, Ph.D. (Medical Director, Staff Pathologist, Assistant Professor)

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  1. Xichun Sun M.D, Ph.D.
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Sun, X. (2015). Cutaneous Tissue. In: Well-Differentiated Malignancies. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1692-4_1

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  • DOI: https://doi.org/10.1007/978-1-4939-1692-4_1

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1691-7

  • Online ISBN: 978-1-4939-1692-4

  • eBook Packages: MedicineMedicine (R0)

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