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Incidence, Trends, and Diagnosis of Perioperative Acute Kidney Injury

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Perioperative Kidney Injury

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Abstract

The incidence of all postoperative acute kidney injury (AKI), including the subset requiring dialysis, is increasing. Modern definitions for AKI, including Risk, Injury, Failure, Loss, and End-Stage Kidney Disease (RIFLE), Acute Kidney Injury Network (AKIN), and Kidney Disease: Improving Global Outcomes (KDIGO), have increased sensitivity and have standardized understanding of AKI, allowing improved epidemiologic study. The reported incidence of AKI following cardiac surgery historically has varied by AKI definition from <1.5 % for cases requiring dialysis to 25 % when AKI is defined as a rise in creatinine of 25 %. AKI rates in noncardiac surgery are significantly lower with the exception of patients in the intensive care unit and those receiving solid organ transplants. Despite rising AKI incidence, multiple studies have found mortality rates in postoperative patients with AKI to either be stable or falling.

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Author information

Authors and Affiliations

  1. Program of Applied Translational Research, Yale-New Haven Medical Center, 60 Temple Street Suite 6C, New Haven, CT, 06510, USA

    Justin M. Belcher MD

  2. Program of Applied Translational Research, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA

    Chirag R. Parikh MD, PhD, FASN

Authors
  1. Justin M. Belcher MD
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  2. Chirag R. Parikh MD, PhD, FASN
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Correspondence to Justin M. Belcher MD .

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Editors and Affiliations

  1. Division of Nephrology and Hypertension, University of Cincinnati, Cincinnati, Ohio, USA

    Charuhas V. Thakar

  2. Program of Applied Translational Research, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

    Chirag R. Parikh

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Belcher, J.M., Parikh, C.R. (2015). Incidence, Trends, and Diagnosis of Perioperative Acute Kidney Injury. In: Thakar, C., Parikh, C. (eds) Perioperative Kidney Injury. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1273-5_1

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  • DOI: https://doi.org/10.1007/978-1-4939-1273-5_1

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  • Online ISBN: 978-1-4939-1273-5

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