Abstract
We model and simulate avascular tumor growth in three dimensions using lattice gas cellular automata (LGCA). Our 3D models are an advance over current state-of-the-art where most three dimensional (3D) models are in fact only a series of two dimensional models simulated to give an appearance of a 3D model. In our 3D model, we use binary description of cells and their states for computational speed and efficiency. The fate and distribution of cells in our model are determined by the Lattice–Boltzmann energy. We simulate our model in a comparable size of lattice and show that the findings are in good agreement with biological tumor behavior.
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Acknowledgements
The first author was a SIRF scholar in Australia and was in receipt of the UIS scholarship during the completion of this research. The financial support of the National Health and Medical Research Council (Australia) Grant No. 1006031 is gratefully acknowledged.
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Shrestha, S.M.B., Joldes, G., Wittek, A., Miller, K. (2014). Modeling Three-Dimensional Avascular Tumor Growth Using Lattice Gas Cellular Automata. In: Doyle, B., Miller, K., Wittek, A., Nielsen, P. (eds) Computational Biomechanics for Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0745-8_2
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DOI: https://doi.org/10.1007/978-1-4939-0745-8_2
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