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A Relationship Between Oxidative Status and Attention Deficit Hyperactivity Disorder

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Studies on Psychiatric Disorders

Abstract

Attention deficit hyperactivity disorder (ADHD) is frequently a chronic disorder, which leads to a negative impact on functioning in both childhood and adulthood. The etiology of ADHD is incompletely understood, but various risk factors including oxidative stress are discussed. Oxidative stress can damage lipids, proteins, and DNA. Last findings showed that the pathophysiology of ADHD may be associated with oxidative stress.

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Abbreviations

ADHD:

Attention deficit hyperactivity disorder

CAT:

Catalase

CSF:

Cerebrospinal fluid

DA:

Dopamine

GSH-Px:

Glutathione peroxidase

MDA:

Malondialdehyde

MPH:

Methylphenidate

NAc:

Nucleus accumbens

NO:

Nitric oxide

OSI:

Oxidative stress index

PUFA:

Polyunsaturated omega-3 fatty acids

PUFAs:

Polyunsaturated fatty acids

ROS:

Reactive oxygen species

SOD:

Superoxide dismutase

TAS:

Total antioxidant status

TOS:

Total oxidative status

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Author information

Authors and Affiliations

  1. Department of Psychiatry, Istanbul Medeniyet University, D-100 Kadikoy, 34700, Istanbul, Turkey

    Salik Selek M.D.

  2. Department of Child and Adolescent Psychiatry, Dr Sami Ulus Children’s Hospital, Ankara, Turkey

    M. Fatih Ceylan M.D.

Authors
  1. Salik Selek M.D.
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  2. M. Fatih Ceylan M.D.
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Correspondence to Salik Selek M.D. .

Editor information

Editors and Affiliations

  1. Department of Biological Psychiatry of the Chair of Experimental and Clinical Physiology, Medical University of Lodz, Lodz, Poland

    Anna Dietrich-Muszalska

  2. Department of Neurochemistry, New York State Institute for Basic Research, Staten Island, New York, USA

    Ved Chauhan

  3. Departments of Psychiatry and Physiology & Biophysics, University of Sherbrooke, Sherbrooke, Quebec, Canada

    Sylvain Grignon

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Selek, S., Ceylan, M.F. (2015). A Relationship Between Oxidative Status and Attention Deficit Hyperactivity Disorder. In: Dietrich-Muszalska, A., Chauhan, V., Grignon, S. (eds) Studies on Psychiatric Disorders. Oxidative Stress in Applied Basic Research and Clinical Practice. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0440-2_7

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