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Intracellular Second Messengers

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Physiology and Pathophysiology of the Islets of Langerhans

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 426))

Abstract

In the β-cell, the effects of extracellular signals are mediated by changes of concentration of intracellular second messengers. Complex interrelationships among the signalling pathways determine the rate of insulin release and also can modulate the rate of insulin biosynthesis. This short overview summarises some key properties of the known second messenger systems of the β-cell. References cited are, where possible, to reviews in order to keep the reference list to a reasonable size.

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Authors and Affiliations

  1. Nuffield Department of Clinical Biochemistry, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK

    Stephen J. H. Ashcroft

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  1. Stephen J. H. Ashcroft
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Editors and Affiliations

  1. Miguel Hernandez University, Alicante, Spain

    Bernat Soria

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Ashcroft, S.J.H. (1997). Intracellular Second Messengers. In: Soria, B. (eds) Physiology and Pathophysiology of the Islets of Langerhans. Advances in Experimental Medicine and Biology, vol 426. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1819-2_9

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  • DOI: https://doi.org/10.1007/978-1-4899-1819-2_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1821-5

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