Abstract
Lithium is a unique and simple agent which has depressant effects on a wide variety of synthetic processes in different organs (Singer and Rotenberg, 1973), and yet has a stimulatory effect on granulopoiesis (Murphy et al., 1971; Tisman et al., 1973; Gupta et al., 1976). Its potential as a therapeutic agent in Felty’s syndrome is now well known, and future uses remain to be clearly defined. Lithium has been reported to stimulate production of colony-stimulating factor (CSF), a putative regulator of granulopoiesis (Gupta et al., 1976; Harker et al., 1977). Lithium has also been reported to enhance the action of CSF (Morley and Galbraith, 1978).
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© 1980 Plenum Press, New York
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Galbraith, P.R. (1980). Effect of Lithium on Colony Formation and Production of Colony-Stimulating Factor. In: Rossof, A.H., Robinson, W.A. (eds) Lithium Effects on Granulopoiesis and Immune Function. Advances in Experimental Medicine and Biology, vol 127. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0259-0_6
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DOI: https://doi.org/10.1007/978-1-4757-0259-0_6
Publisher Name: Springer, Boston, MA
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