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Double-Label Quantitative Autoradiographic Studies of Anaerobic Glucose Metabolism in Limbic Seizures

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Kindling 4

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 37))

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Abstract

Sokoloff’s (1) radiolabeled 2-deoxyglucose (2DG) method for calculating the local cerebral metabolic rate for glucose (LCMR) has been employed to determine those structures most involved in a variety of experimental and clinical paradigms. It has proven particularly valuable in identifying the structures most involved in a number of human and animal seizure states (2).

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Author information

Authors and Affiliations

  1. Division of Nuclear Medicine and Biophysics, Department of Radiological Sciences; Department of Neurology, Laboratory of Biomedical and Environmental Sciences and Brain Research Institute, UCLA School of Medicine, Los Angeles, CA, 90024, USA

    Robert F. Ackermann

  2. Division of Nuclear Medicine, Department of Radiology, University of Colorado Center for Health Sciences, 4200 E. 9th Ave., Denver, CO, 80262, USA

    James L. Lear

Authors
  1. Robert F. Ackermann
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  2. James L. Lear
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Editors and Affiliations

  1. Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, Canada

    Juhn A. Wada

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© 1990 Plenum Press, New York

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Ackermann, R.F., Lear, J.L. (1990). Double-Label Quantitative Autoradiographic Studies of Anaerobic Glucose Metabolism in Limbic Seizures. In: Wada, J.A. (eds) Kindling 4. Advances in Behavioral Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5796-4_6

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  • DOI: https://doi.org/10.1007/978-1-4684-5796-4_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5798-8

  • Online ISBN: 978-1-4684-5796-4

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