Abstract
The direct stimulus for vertebrate sensory hair cells is, in general, provided by fluid surrounded macrostructures that are coupled mechanically to the hair bundles. The dynamic behaviour of these accessory structures is determined by their hydrodynamic and mechanical characteristics. A considerable part of the mechanical suspension of these structures is probably provided by the hair bundles. The micromechanical properties of the hair cells are therefore thought to contribute significantly to the mechanical characteristics of these accessory structures and to influence their motion (Khanna and Leonard, 1982; Flock and Strelioff, 1984; Strelioff et al., 1984). In the mammalian cochlea, for instance, hair cell properties are assumed to be responsible for the sharp tuning of the basilar membrane (Khanna and Leonard, 1986).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Flock, Å. (1971) Sensory transduction in hair cells. In: Handbook of sensory physiology Vol.1 (Ed: Loewenstein, W.R.) Springer Verlag, Berlin, pp. 396–441.
Flock, Å and Strelioff, D. (1984) Graded and nonlinear mechanical properties of sensory hairs in the mammalian hearing organ. Nature 310, 597–599.
Howard, J and Ashmore, J.H. (1986) Stiffness of sensory hair bundles in the sacculus of the frog. Hearing Res. 23, 93–104.
Howard, J. and Hudspeth, A.J. (1987) Mechanical relaxation of the hair bundles mediates adaptation in mechanoelectrical transduction by the bullfrog’s saccular hair cell. Proc. Natl. Acad. Sci. USA 84, 3064–3068.
Howard, J. and Hudspeth, A.J. (1988) Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog’s saccular hair cell. Neuron. 1, 189–199.
Hudspeth, A.J. and Kroese, A.B.A. (1983) Voltage-dependent interaction of dihydrostreptomycin with the transduction channels in bullfrog sensory hair cells. J.Physiol. 345, 66P.
Khanna, S.M. and Leonard, D.G.B. (1982) Basilar membrane tuning in the cat cochlea. Science 215, 305–306.
Khanna, S.M. and Leonard, D.G.B. (1986) Relationship between basilar membrane tuning and hair cell condition. Hearing Res. 23, 55–70.
Kroese, A.B.A. and Bercken, J. van den (1980) Dual action of ototoxic antibiotics on sensory hair cells. Nature 283, 395–397.
Kroese, A.B.A. and Bercken, J. van den (1982) Effects of ototoxic antibiotics on sensory hair cell functioning. Hearing Res. 6, 183–197.
Kroese, A.B.A. and Netten, S.M. van (1987) The application of incident light polarization microscopy for the visualization of sensory hair cells in vivo. J. Microsc. 145, 309–317.
Kroese, A.B.A. and Netten, S.M. van (1988) Sensory transduction in lateral line sensory hair cells. In: Neurobiology and evolution of the lateral line. (Eds: Coombs, S., Görner, P. and Münz, H.) Springer Verlag, New York. In press.
Kroese, A.B.A. Das, A. and Hudspeth, A.J. (1988) Blockage of the transduction channels of hair cells in the bullfrog’s sacculus by aminoglycoside antibiotics. Submitted for publication.
Netten, S.M. van (1987) Laser interferometric study of the mechanosensitivity of the fish lateral line. Thesis, University of Groningen, Groningen.
Netten, S.M. van (1988a) Laser interferometer microscope for the measurement of nanometer vibrational displacements of a light-scattering microscopic object. J. Acoust. Soc. Am. 83, 1667–1674.
Netten, S.M. van (1988b) Hydrodynamics of the excitation of the cupula in the fish canal lateral line. Submitted for publication.
Netten, S.M. van and Kroese, A.B.A. (1987) Laser interferometric measurements on the dynamic behaviour of the cupula in the fish lateral line. Hearing Res. 29, 55–61.
Netten, S.M. van and Kroese, A.B.A. (1988) Dynamic behaviour and micromechanical properties of the cupula. In: Neurobiology and evolution of the lateral line. (Eds: Coombs, S., Görner, P. and Münz, H.) Springer Verlag, New York. In press.
Ohmori, H. (1985) Mechano-electrical transduction currents in isolated vestibular hair cells of chick. J. Physiol. 359, 189–217.
Pickles, J.O. Comis, S.D. and Osborne, M.P. (1984) Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction. Hearing Res. 15, 103–112.
Pickles, J.O. Comis, S.D. and Osborne, M.P. (1987) The effect of chronic application of kanamycin on stereocilia and their tip links in hair cells of the guinea pig cochlea. Hearing Res. 29, 237–244.
Richardson, G.P., Russell, I.J., Wasserkort, R. and Hans, M. (1988) Aminoglycoside antibiotics and lectins cause irreversible increases in the stiffness of cochlear hair-cell stereocilia. “Mechanics of Hearing” proceedings, Eds: Wilson, J.P. and Kemp, D.T. (This volume).
Strelioff, D., Flock, Å. and Minser, K.E. (1985) Role of outer hair cells in mechanical frequency selectivity of the cochlea. Hearing Res. 18, 169–175.
Wersäll, J. and Flock, Å. (1964) Suppression and restoration of the microphonic output from the lateral line organ after local application of streptomycin. Life Sci. 3, 1151–1155.
Harris, G.T. and Milne, D.C. (1966) Input-output characteristics of the lateral-line sense organs of Xenopus laevis, JASA, 40, 32–42.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Plenum Press, New York
About this chapter
Cite this chapter
van Netten, S.M., Kroese, A.B.A. (1989). Hair Cell Mechanics Controls the Dynamic Behaviour of the Lateral Line Cupula. In: Wilson, J.P., Kemp, D.T. (eds) Cochlear Mechanisms: Structure, Function, and Models. NATO ASI Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5640-0_6
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5640-0_6
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5642-4
Online ISBN: 978-1-4684-5640-0
eBook Packages: Springer Book Archive