Skip to main content

Expression of Preprosomatostatin in Foreign Cells: Secretion of Mature Somatostatin by Yeast (Saccharomyces Cerevisiae)

  • Chapter
Somatostatin

Part of the book series: Serono Symposia, USA ((SERONOSYMP))

  • 59 Accesses

Abstract

Most small peptide hormones are synthesized as part of larger precursors which undergo proteolytic processing to generate the bioactive peptides (1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Douglass J, Civelli 0, Herbert E. Annu Rev Biochem 1984; 53: 665–715.

    Article  CAS  Google Scholar 

  2. Shields D, Blobel G. Proc Natl Acad Sci USA 1977; 74: 2059–63.

    Article  PubMed  CAS  Google Scholar 

  3. Shields D. Proc Natl Acad Sci USA 1980; 77: 4074–8.

    Article  PubMed  CAS  Google Scholar 

  4. Steiner DF, Quinn PS, Chan SJ, Makh J, Tager HS. Ann NY Acad Sci 1980; 343: 1–39.

    Article  PubMed  CAS  Google Scholar 

  5. Reichlin S. N Engl J Med 1983; 309: 1495–1501.

    Article  PubMed  CAS  Google Scholar 

  6. Warren TG, Shields D. Biochemistry 1984; 23: 2684–90.

    Article  PubMed  CAS  Google Scholar 

  7. Goodman RH, Aron DC, Roos BA. J Biol Chem 1983; 258: 5570–3.

    PubMed  CAS  Google Scholar 

  8. Hobart P, Crawford R, LuPing S, Raymond P, Rutter WJ. Nature 1980; 288: 137–41.

    Article  PubMed  CAS  Google Scholar 

  9. Noe BD, Debo G, Spiess J. J Cell Biol 1984; 99: 578–87.

    Article  PubMed  CAS  Google Scholar 

  10. Warren TG, Shields D. Cell 1984; 39: 547–55.

    Article  PubMed  CAS  Google Scholar 

  11. Novick P, Field C, Schekman R. Cell 1980; 21: 205–15.

    Article  PubMed  CAS  Google Scholar 

  12. Kurjan J, Herzkowitz I. Cell 1982; 30: 933–43.

    Article  PubMed  CAS  Google Scholar 

  13. Julius D, Schekman R, Thorner J. Cell 1984; 36: 309–18.

    Article  PubMed  CAS  Google Scholar 

  14. Julius D, Brake A, Blair L, Kunisawa R, Thorner J. Cell 1984; 37: 1075–89.

    Article  PubMed  CAS  Google Scholar 

  15. Achstetter T, Wolf DH. EMBO J 1984; 4: 173-7.

    Google Scholar 

  16. Julius D, Blair L, Brake A, Sprague G, Thorner J. Cell 1983; 32: 839–52.

    Article  PubMed  CAS  Google Scholar 

  17. Bitter GA, Chen KK, Banks AR, Lai P-H. Proc Natl Acad Sci USA 1984; 81: 5330–4.

    Article  PubMed  CAS  Google Scholar 

  18. Singh A, Lugovoy JM, Kohn WJ, Perry LJ. Nucleic Acids Res 1984; 12: 8927–38.

    Article  PubMed  CAS  Google Scholar 

  19. Brake A, Merryweather JP, Coit DG, et al. Proc Natl Acad Sci USA 1984; 81: 4642–6.

    Article  PubMed  CAS  Google Scholar 

  20. Kramer RA, Anderson N. Proc Natl Acad Sci USA 1980; 7: 6541–5.

    Article  Google Scholar 

  21. Andersen N, Thill GP, Kramer RA. Mol Cell Biol 1983; 3: 562–9.

    PubMed  CAS  Google Scholar 

  22. Schaber MD, DeChiara TM, Kramer RH. Methods Enzymol 1986; 119: 4 1723

    Google Scholar 

  23. Hinnen A, Hicks JB, Fink GR. Proc Natl Acad Sci USA 1978; 75: 19 2933

    Google Scholar 

  24. Jones E. Genetics 1977; 85: 23–33.

    PubMed  CAS  Google Scholar 

  25. Morinaga Y, Franceschini T, Inouye S, Inouye M. Biotechnol 1984; 2: 636–9.

    Article  CAS  Google Scholar 

  26. Kramer RH, DeChiara TM, Schaber MD, Hilliker S. Proc Nati Acad Sci USA 1984; 81: 367–70.

    Article  CAS  Google Scholar 

  27. Speiss J, Villarreal J, Vale W. Biochemistry 1981; 20: 1982–8.

    Article  Google Scholar 

  28. Green R, Shields D. Endocrinology 1984; 114: 1990–4.

    Article  PubMed  CAS  Google Scholar 

  29. Sripati, Warner J. Methods Cell Biol 1978; 20: 61.

    Article  PubMed  Google Scholar 

  30. Poruchynsky MS, Tyndall C, Both GW, Sato F, Bellamy R, Atkinson PH. J Cell Biol 1985; 101: 2199–2209.

    Article  PubMed  CAS  Google Scholar 

  31. Tarentino AL, Maley F. J Biol Chem 1974; 249: 811–7.

    PubMed  CAS  Google Scholar 

  32. Blobel G. Proc Natl Acad Sci USA 1980; 77: 1496–1500.

    Article  PubMed  CAS  Google Scholar 

  33. Sabatini DD, Kreibich G, Morimoto T, Adesnik M. J Cell Biol 1982; 92: 1–22.

    Article  PubMed  CAS  Google Scholar 

  34. Lingappa VR, Chaidez J, Yost CS, Hedgpeth J. Proc Natl Acad Sci USA 1984; 81: 456–60.

    Article  PubMed  CAS  Google Scholar 

  35. Green R, Schaber M, Shields D, Kramer R. J Biol Chem 1986 (in press).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer Science+Business Media New York

About this chapter

Cite this chapter

Shields, D., Green, R., Schaber, M., Kramer, R. (1987). Expression of Preprosomatostatin in Foreign Cells: Secretion of Mature Somatostatin by Yeast (Saccharomyces Cerevisiae). In: Reichlin, S. (eds) Somatostatin. Serono Symposia, USA. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5326-3_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5326-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5328-7

  • Online ISBN: 978-1-4684-5326-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics