Abstract
The acetylcholine receptor (AcChoR) is one of the best known membrane-bound allosteric proteins (reviewed by Changeux, 1981; Changeux et al., 1984). Integrated in the post-synaptic membrane of the cholinergic synapse (neuromuscular junction, electromotor synapse), it regulates the opening of a cation-selective ionic channel upon binding of the neurotransmitter (acetylcholine). In the course of the past fifteen years, the protein assembly which carries both the acetylcholine binding sites and the ion channel has been isolated and purified from fish (Electrophorus, Torpedo) electric organ and vertebrate muscle.
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© 1984 Plenum Press, New York
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Devillers-Thiery, A., Giraudat, J., Bentaboulet, M., Klarsfeld, A., Changeux, J.P. (1984). Molecular Genetics of Torpedo Marmorata Acetylcholine Receptor. In: Lauder, J.M., Nelson, P.G. (eds) Gene Expression and Cell-Cell Interactions in the Developing Nervous System. Advances in Experimental Medicine and Biology, vol 181. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4868-9_3
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DOI: https://doi.org/10.1007/978-1-4684-4868-9_3
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