Abstract
Chimeras can be either of mixed chromosomal sex, XX ↔ XY, or they can be single-sex, XX ↔ XX or XY ↔ XY. If the sex ratio at the time of chimera formation is unity, mixed-sex and single-sex chimeras will be expected to occur in equal numbers. The data available from chromosomal sexing of chimera components suggest that this expectation is fulfilled (McLaren 1976). The problems of XX ↔ XY animals, both from the point of view of sexual differentiation, and as regards the fate of their germ cells, are considered elsewhere in this volume. In this paper I shall restrict myself to single-sex chimeras and their germ cells.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Anderson, E. and D. F. Albertini. 1976. Gap junctions between the oocyte and companion follicle cells in the mammalian ovary. J. Cell Biol. 71: 680–686.
Beatty, R. A. 1969. A genetic study of spermatozoan dimensions in mice selected for body weight. Ind. J. Hered. 1: 2–21.
Beatty, R. A. and K. N. Sharma. 1960. Genetics of gametes. III Strain differences in spermatozoa from eight inbred strains of mice. Proc. Roy. Soc. Edinburgh B, 68: 25–53.
Burgoyne, P. S. 1973. The genetic control of germ cell differentiation in mice. Ph.D. Thesis, University of Edinburgh.
Burgoyne, P. S. 1975. Sperm phenotype and its relationship to somatic and germ line genotype: a study using mouse aggregation chimeras. Dev. Biol. 44: 63–76.
Fawcett, D. W., W. A. Anderson and D. M. Phillips. 1971. Morphogenese factors influencing the shape of the sperm head. Dev. Biol. 26: 220–251.
Ford, C. E., E. P. Evans, M. D. Burtenshaw, H. M. Clegg, M. Tuffrey and R. D. Barnes. 1975. A functional fsex-reversedf oocyte in the mouse. Proc. Roy. Soc. Lond. B. 190: 187–197.
Kanazawa, K. and A. Imai. 1974. Parasexual-sexual hybridization — heritable transformation of germ cells in chimeric mice. Jap. J. Exp. Med. 44: 227–234.
Krzanowska, H. 1976. Inheritance of sperm head abnormality types in mice — the role of the Y chromosome. Genet. Res. 28: 189–198.
Lyon, M. F., P. H. Glenister and M. L. Lamoreux. 1975. Normal spermatozoa from androgen-resistant germ cells of chimaeric mice and the role of androgen in spermatogenesis. Nature 258: 620–622.
McLaren, A. 1975a. The independence of germ-cell genotype from somatic influence in chimaeric mice. Genet. Res. 25: 83–87.
McLaren, A. 1975b. Sex chimaerism and germ cell distribution in a series of chimaeric mice. J. Embryol. exp. Morph. 33: 205–216.
McLaren, A. 1976. Mammalian Chimaeras. Cambridge University Press.
Mintz, B. 1968. Hermaphrodism, sex chromosomal mosaicism and germ cell selection in allophenic mice. J. Anim. Sci. (Suppl. 1), 27: 51–60.
Mintz, B. 1969. Developmental mechanisms found in allophenic mice with sex chromosomal and pigmentary mosaicism. Birth Defects: Original Article Series 5: 11–22. In: First Conference on the Clinical Delineation of Birth Defects, ed. D. Bergsma and V. McKusick. New York: National Foundation.
Mullen, R. J. and W. K. Whitten. 1971. Relationship of genotype and degree of chimerism in coat color to sex ratios and gametogene-sis in chimeric mice. J. exp. Zool. 178: 165–176.
Mystkowska, E. T. and A. K. Tarkowski. 1968. Observations on CBA-p/CBA-T6T6 mouse chimaeras. J. Embryol. exp. Morph. 20: 33–52.
Nagano, T. 1968. Fine structural relation between the Sertoli cell and the differentiating spermatid in the human testis. Z. Zellforsch. 89: 39–43.
Phillips, D. M. 1970. Development of spermatozoa in the woolly opossum with special reference to the shaping of the sperm head. J. Ultrastruct. Res. 33: 369–380.
Szöllösi, D., M. Gérard, Y. Ménézo and C. Thibault. 1978. Permeability of ovarian follicle; corona cell-oocyte relationship in mammals. Ann. Biol. anim. Biochem. Biophys. 18(2), in press.
Weir, J. A. 1976. Allosomal and autosomal control of sex ratio in PHH and PHL mice. Genetics 84: 755–764.
Williams, D. A., R. A. Beatty and P. S. Burgoyne. 1970. Multivariate analysis in the genetics of spermatozoan dimensions in mice. Proc. Roy. Soc., B 175: 313–331.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Plenum Press, New York
About this chapter
Cite this chapter
McLaren, A. (1978). Reproduction in Single-Sex Chimeras. In: Russell, L.B. (eds) Genetic Mosaics and Chimeras in Mammals. Basic Life Sciences, vol 12. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3390-6_10
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3390-6_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3392-0
Online ISBN: 978-1-4684-3390-6
eBook Packages: Springer Book Archive