Skip to main content
SpringerLink
Log in

The Primary Structure of Histones and Protamines

  • Chapter
Histones and Nucleohistones

Abstract

The year 1969 marked the publication of the complete amino acid sequence of two of the major histones, the F2A1(IV) histone of calf thymus and of pea embryos, and the F2B(IIb2) histone of calf thymus. Publication of a partial sequence of an Fl(I) histone from rabbit thymus followed in 1970 and it is known that work is in progress on the sequences of the histones F3(III) and F2A2(IIbl) of calf thymus and the histone F2C(V) peculiar to nucleated erythrocytes and reticulocytes. Another notable achievement during the period from 1962 to the present was the elucidation of the complete amino acid sequences of seven of the protamines.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. P. G. Butler, J. I. Harris, B. S. Hartley and R. Leberman, Biochem. J., 103, 78P (1967)

    Google Scholar 

  2. C. H. Li and L. Bertsch, J. Biol. Chem., 235, 2638 (1960)

    PubMed  CAS  Google Scholar 

  3. L. S. Hnilica, H. A. Kappler and J. J. Jordan, Experientia (In press)

    Google Scholar 

  4. K. Iwai, K. Ishikawa and H. Hayashi, Histones and Gene Function (K. Iwai, ed.), p. 11. “The Research Group on Histones and Gene Function in Japan” (1969)

    Google Scholar 

  5. R. J. DeLange, D. M. Fambrough, E. L. Smith and J. Bonner, J. Biol. Chem., 244, 319 (1969)

    PubMed  CAS  Google Scholar 

  6. D. M. P. Phillips and P. Simson, Unpublished observations

    Google Scholar 

  7. M. Flavin and C. Slaughter, Biochemistry, 4, 1370 (1965)

    Article  PubMed  CAS  Google Scholar 

  8. H. Matsubara, A. Singer, R. Sasaki and T. H. Jukes, Biochem. Biophys. Res. Commun., 21, 242 (1965)

    Article  PubMed  CAS  Google Scholar 

  9. T. Ando and S. Watanabe, Int. J. Protein Res., 1, 221 (1969)

    Article  PubMed  CAS  Google Scholar 

  10. G. Quagliarotti, Y. Ogawa, C. W. Taylor, P. Sautiere, J. Jordan, W. C. Starbuck and H. Busch, J. Biol. Chem., 244, 1796 (1969)

    PubMed  CAS  Google Scholar 

  11. M. Bustin, S. C. Rall, R. H. Stellwagen and R. D. Cole, Science, 163, 391 (1969)

    Article  PubMed  CAS  Google Scholar 

  12. K. Satake, P. S. Rasmussen and J. M. Luck, J. Biol. Chem. 235, 2801 (1960)

    CAS  Google Scholar 

  13. E. L. Gershey, G. Vidali and V. G. Allfrey, J. Biol. Chem., 243, 5018 (1968)

    PubMed  CAS  Google Scholar 

  14. M. Bustin and R. D. Cole, J. Biol. Chem., 244, 5286 (1969)

    PubMed  CAS  Google Scholar 

  15. D. M. P. Phillips and P. Simson, Biochim. Biophys. Acta, 181, 154, (1969)

    PubMed  CAS  Google Scholar 

  16. E. Gross and B. Witkop, J. Biol. Chem., 237, 1856 (1962)

    PubMed  CAS  Google Scholar 

  17. R. J. DeLange, D. M. Fambrough, E. L. Smith and J. Bonner, J. Biol. Chem., 243, 5906 (1968)

    PubMed  CAS  Google Scholar 

  18. G. Biserte, M. Bonte, P. Sautiere, A. Martinage, Y. Moschetto and P. Boulanger, J. Chromatog., 35, 168 (1968)

    Article  CAS  Google Scholar 

  19. L. K Ramachandran and B. Witkop, Methods in Enzymology (S. P. Colowick and N. O. Kaplan, eds), 11, p. 283. Academic Press, New York (1967)

    Google Scholar 

  20. M. Bustin and R. D. Cole, J. Biol. Chem., 244, 5291 (1969)

    PubMed  CAS  Google Scholar 

  21. T. Ando, K. Iwai, S-I. Ishii, M. Azegami and C. Nakahara, Biochim. Biophys. Acta, 56, 628 (1962)

    Article  PubMed  CAS  Google Scholar 

  22. J. M. Luck, K. Satake, P. S. Rasmussen and A. N. Tsvetikov, J. Biol. Chem., 233, 1407 (1958)

    PubMed  CAS  Google Scholar 

  23. E. W. Johns, D. M. P. Phillips, P. Simson and J. A. V. Butler, Biochem. J., 77, 631 (1960)

    PubMed  CAS  Google Scholar 

  24. K. Murray, Ann. Rev. Biochem., 34, 209 (1965)

    Article  PubMed  CAS  Google Scholar 

  25. K. Murray, The Nucleohistones (J. Bonner and P. O. Ptso, eds), p. 21. Holden-Day Inc., San Francisco, London, Amsterdam (1964)

    Google Scholar 

  26. D. C. Teller, J. M. Kinkade and R. D. Cole, Biochem. Biophys. Res. Commun., 20, 739 (1965)

    Article  PubMed  CAS  Google Scholar 

  27. M. Bustin and R. D. Cole, J. Biol. Chem., 243, 4500 (1968)

    PubMed  CAS  Google Scholar 

  28. J. M. Kinkade, J. Biol. Chem., 244, 3375 (1969)

    PubMed  CAS  Google Scholar 

  29. J. M. Kinkade and R. D. Cole, J. Biol. Chem., 241, 5790 (1966)

    PubMed  CAS  Google Scholar 

  30. J. C. Rall and R. D. Cole, Unpublished observations

    Google Scholar 

  31. R. D. Cole, Unpublished observations

    Google Scholar 

  32. M. O. Dayhoff and R. V. Eck, Atlas of Protein Sequence and Structure, National Biomedical Research Foundation, Silver Spring, Maryland, U.S.A. (1967–68)

    Google Scholar 

  33. D. M. P. Phillips, Biochem. J., 87, 258 (1963)

    PubMed  CAS  Google Scholar 

  34. D. M. Fambrough, Handbook of Molecular Cytology (A. Lima-De-Faria, ed.), p. 437. North-Holland Publishing Co., Amsterdam and London (1969)

    Google Scholar 

  35. T. N. Langan, J. Biol. Chem., 244, 5763 (1969)

    PubMed  CAS  Google Scholar 

  36. G. H. Dixon, K. Marushige, V. Ling, M. Sung and D. T. Wigle, Federation Proc., 28, 599 (1969)

    Google Scholar 

  37. D. C. Lamb, P. X. Callahan, N. L. Brenner and K. Murray, Unpublished observations

    Google Scholar 

  38. J. M. Kinkade and R. D. Cole, J. Biol. Chem., 241, 5798 (1966)

    PubMed  CAS  Google Scholar 

  39. L. S. Hnilica, Progr. Nucleic Acid Res. and Mol. Biol., 7, 25 (1967)

    Article  CAS  Google Scholar 

  40. J. A. V. Butler, E. W. Johns and D. M. P. Phillips, Progr. Biophys. and Mol. Biol., 18, 211 (1968)

    Google Scholar 

  41. L. S. Hnilica, Biochim. Biophys. Acta, 117, 163 (1966)

    Article  PubMed  CAS  Google Scholar 

  42. E. M. Bradbury, Biochem. J., 114, 49P (1969)

    Google Scholar 

  43. D. M. P. Phillips and M. Clarke, J. Chromatog., 46, 320 (1970)

    Article  CAS  Google Scholar 

  44. D. M. P. Phillips, Biochem. J., 107, 135 (1968)

    PubMed  CAS  Google Scholar 

  45. R. J. DeLange, D. M. Fambrough, E. L. Smith and J. Bonner, J. Biol. Chem., 244, 5669 (1969)

    PubMed  CAS  Google Scholar 

  46. H. J. Gruft, J. Hindley, C. M. Mauritzen and E. Stedman, Nature, 180, 1107 (1957)

    Article  Google Scholar 

  47. V. A. Blazsek and L. Bukaresti, Experientia, 20, 369 (1964)

    Article  PubMed  CAS  Google Scholar 

  48. D. M. P. Phillips, Biochem. J., 97, 669 (1965)

    PubMed  CAS  Google Scholar 

  49. E. Jellum, Biochim. Biophys. Acta, 115, 95 (1966)

    Article  PubMed  CAS  Google Scholar 

  50. K. Yokotsuka and K. Shimura, Histones and Gene Function (K. Iwai, ed.), p. 20. “The Research Group on Histones and Gene Function in Japan” (1969)

    Google Scholar 

  51. D. M. Fambrough and J. Bonner, J. Biol. Chem., 243, 4434 (1968)

    PubMed  CAS  Google Scholar 

  52. D. M. P. Phillips, Biochem. J., 105, 46P (1967)

    CAS  Google Scholar 

  53. D. P. Bloch, Genetics Supplement, 61, (1), p. 93 (1969)

    CAS  Google Scholar 

  54. T. Ando and K. Suzuki, Biochim. Biophys. Acta, 121, 427 (1966)

    Article  PubMed  CAS  Google Scholar 

  55. T. Ando and K. Suzuki, Biochim. Biophys. Acta, 140, 375 (1967)

    PubMed  CAS  Google Scholar 

  56. C. J. Ingles and G. H. Dixon, Proc. Nat. Acad. Sci.,U.S., 58, 1011 (1967)

    Article  CAS  Google Scholar 

  57. G. H. Dixon and M. Smith, Progr. Nucleic Acid. Res. and Mol. Biol., 8, 9 (1968)

    Article  CAS  Google Scholar 

  58. J. A. Black and G. H. Dixon, Nature, 216, 152 (1967)

    Article  PubMed  CAS  Google Scholar 

  59. O. Smithies, G. E. Connell and G. H. Dixon, Nature, 196, 232 (1962)

    Article  PubMed  CAS  Google Scholar 

  60. E. Margoliash and E. L. Smith, Evolving Genes and Proteins (V. Bryson and H. J. Vogel, eds), p. 221. Academic Press, New York (1965)

    Google Scholar 

  61. W. N. Selander and J. M. Blair, Unpublished observations. (The author is greatly indebted to Dr. Selander and Dr. Blair for their help in this problem.)

    Google Scholar 

  62. G. Braunitzer, K. Hilse, V. Rudloff and N. Hilschmann, Advan. Protein Chem., 19, 1 (1964)

    Article  CAS  Google Scholar 

  63. G. H. Dixon, Essays in Biochemistry (P. N. Campbell and G. D. Greville, eds), 2, 147. Academic Press, London and New York (1966)

    Google Scholar 

  64. R. Vendrely, A. Knobloch-Mazen and C. Vendrely, The Cell Nucleus, p. 20. Butterworths Scientific Publications, London (1960)

    Google Scholar 

  65. V. C. Littau, C. J. Burdick, V. G. Allfrey and A. E. Mirsky, Proc. Nat. Acad. Sci., U.S., 54, 1204 (1965)

    Article  CAS  Google Scholar 

  66. E. W. Johns, Biochem. J., 92, 55 (1964)

    PubMed  CAS  Google Scholar 

  67. B. Low, F. M. Lovell and A. D. Rudko,Proc. Nat. Acad. Sci., U.S., 60, 1519 (1968)

    Article  CAS  Google Scholar 

  68. M. Feughelman, R. Langridge, W. E. Seeds, A. R. Stokes, H. R. Wilson, C. W. Hooper, M. H. F. Wilkins, R. K. Barclay and L. D. Hamilton, Nature, 175, 834 (1955)

    Article  PubMed  CAS  Google Scholar 

  69. M. H. F. Wilkins, Rapp. Cons. Chim. Solvay, 11, 45 (1959)

    Google Scholar 

  70. F. Klein and J. A. Szirmai, Biochim. Biophys. Acta, 72, 48 (1963)

    Article  PubMed  CAS  Google Scholar 

  71. A. Miura and Y. Ohba, Biochim. Biophys. Acta, 145, 436 (1967)

    PubMed  CAS  Google Scholar 

  72. D. M. P. Phillips, Unpublished observations

    Google Scholar 

  73. J. Paul and R. S. Gilmour, J. Mol. Biol., 16, 242 (1966)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3, UK

    D. M. P. Phillips

  2. Division of Biology and Health Physics, Chalk River Nuclear Laboratories, Atomic Energy of Canada Limited, Chalk River, Ontario, Canada

    D. M. P. Phillips

Authors
  1. D. M. P. Phillips
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, London S.W.3, UK

    D. M. P. Phillips

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Plenum Publishing Company Ltd.

About this chapter

Cite this chapter

Phillips, D.M.P. (1971). The Primary Structure of Histones and Protamines. In: Phillips, D.M.P. (eds) Histones and Nucleohistones. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1815-6_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-1815-6_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1817-0

  • Online ISBN: 978-1-4684-1815-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation