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Chromosome Structural Aberrations

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Human Chromosomes

Part of the book series: Springer Study Edition ((SSE))

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Abstract

Chromosome breaks sometimes occur spontaneously, or they may be induced by a mutagenic agent such as ionizing radiation or DNA-damaging chemicals. Unlike normal chromosome ends, broken ends tend to join together. Usually the broken ends rejoin; in other words, the break heals. However, a break may lead to a deletion or, if more than one break has occurred in a cell, to structural rearrangements of chromosomes.

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Authors and Affiliations

  1. Department of Medical Genetics, University of Wisconsin, Madison, WI, 53706, USA

    Eeva Therman

  2. Medical School, University of Wisconsin, Madison, WI, 53706, USA

    Millard Susman

Authors
  1. Eeva Therman
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  2. Millard Susman
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© 1993 Springer-Verlag New York, Inc.

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Therman, E., Susman, M. (1993). Chromosome Structural Aberrations. In: Human Chromosomes. Springer Study Edition. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0529-3_9

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  • DOI: https://doi.org/10.1007/978-1-4684-0529-3_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-97871-0

  • Online ISBN: 978-1-4684-0529-3

  • eBook Packages: Springer Book Archive

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