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Origins and Directions of Human Cytogenetics

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Human Chromosomes

Part of the book series: Springer Study Edition ((SSE))

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Abstract

Before 1956 two “facts” were known about human cytogenetics. The human chromosome number was believed to be 48, and the XX-XY mechanism of sex determination was assumed to work in the same way as it does in Drosophila. Studies of the fruit fly had shown that the ratio of the number of X chromosomes to the number of sets of autosomes determines the sex of the organism. Both of these fundamental notions about human chromosomes were eventually proved wrong.

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Authors and Affiliations

  1. Department of Medical Genetics, University of Wisconsin, Madison, WI, 53706, USA

    Eeva Therman

  2. Medical School, University of Wisconsin, Madison, WI, 53706, USA

    Millard Susman

Authors
  1. Eeva Therman
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  2. Millard Susman
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© 1993 Springer-Verlag New York, Inc.

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Therman, E., Susman, M. (1993). Origins and Directions of Human Cytogenetics. In: Human Chromosomes. Springer Study Edition. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0529-3_1

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  • DOI: https://doi.org/10.1007/978-1-4684-0529-3_1

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-97871-0

  • Online ISBN: 978-1-4684-0529-3

  • eBook Packages: Springer Book Archive

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